| 研究課題/領域番号 |
22K17847
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| 研究種目 |
若手研究
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| 配分区分 | 基金 |
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| 審査区分 |
小区分59040:栄養学および健康科学関連
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| 研究機関 | 国立研究開発法人国立長寿医療研究センター |
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研究代表者 |
張 シュ 国立研究開発法人国立長寿医療研究センター, 研究所 老年学・社会科学研究センター, 研究員 (00874471)
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| 研究期間 (年度) |
2022-04-01 – 2026-03-31
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| 研究課題ステータス |
交付 (2023年度)
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| 配分額 *注記 |
4,550千円 (直接経費: 3,500千円、間接経費: 1,050千円)
2025年度: 520千円 (直接経費: 400千円、間接経費: 120千円)
2024年度: 910千円 (直接経費: 700千円、間接経費: 210千円)
2023年度: 1,300千円 (直接経費: 1,000千円、間接経費: 300千円)
2022年度: 1,820千円 (直接経費: 1,400千円、間接経費: 420千円)
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| キーワード | risk factors / cognitive frailty / cohort / dietary diversity / nutritional approach |
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| 研究開始時の研究の概要 |
This study uses interdisciplinary data to elucidate: 1) dietary factors that play important roles in preventing cognitive frailty; 2) possible mechanisms of any associations identified; and 3) risk factors modifying nutrition approaches for preventing and improving cognitive frailty.
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| 研究実績の概要 |
This study aims to elucidate: 1) dietary factors that play important roles in preventing cognitive frailty (CF) (through different pathways); 2) possible mechanisms of any associations identified; and 3) risk factors modifying nutrition approaches for preventing and improving CF.
My main task this year was to collect data on subjective cognitive decline using the Memory Complaint Questionnaire in Japanese (MAC-Q-J) in the NILS-LSA 10th wave survey. In addition, I examined the effects of various risk factors on the transition from robustness to CF using 14 years of cognitive function and frailty data. I found differences in the effects of different risk factors on the transition pathways in a multi-state model. This result suggests the need for targeted interventions for CF prevention.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
The 10th survey is well underway and gathering useful information for further analysis. It provides useful data for defining CF in the future.
Based on the existing risk factor assessment data and 14 years of cognitive function and frailty data, I was able to secure a certain number of subjects and examine association between risk factors and CF development. The findings obtained will be submitted to international academic journals.
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| 今後の研究の推進方策 |
I will utilize the data collected using the MAC-Q in the new round of the NILS-LSA survey (10th) to more accurately determine the CF status of the participants. These data will be further analyzed.
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