研究課題/領域番号 |
22K17847
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研究種目 |
若手研究
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配分区分 | 基金 |
審査区分 |
小区分59040:栄養学および健康科学関連
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研究機関 | 国立研究開発法人国立長寿医療研究センター |
研究代表者 |
張 シュ 国立研究開発法人国立長寿医療研究センター, 研究所 老年学・社会科学研究センター, 研究員 (00874471)
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研究期間 (年度) |
2022-04-01 – 2026-03-31
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研究課題ステータス |
交付 (2022年度)
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配分額 *注記 |
4,550千円 (直接経費: 3,500千円、間接経費: 1,050千円)
2025年度: 520千円 (直接経費: 400千円、間接経費: 120千円)
2024年度: 910千円 (直接経費: 700千円、間接経費: 210千円)
2023年度: 1,300千円 (直接経費: 1,000千円、間接経費: 300千円)
2022年度: 1,820千円 (直接経費: 1,400千円、間接経費: 420千円)
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キーワード | dietary diversity / cognitive frailty / cohort / nutritional approach |
研究開始時の研究の概要 |
This study uses interdisciplinary data to elucidate: 1) dietary factors that play important roles in preventing cognitive frailty; 2) possible mechanisms of any associations identified; and 3) risk factors modifying nutrition approaches for preventing and improving cognitive frailty.
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研究実績の概要 |
This study aims to elucidate: 1) dietary factors that play important roles in preventing cognitive frailty (CF) (through different pathways); 2) possible mechanisms of any associations identified; and 3) risk factors modifying nutrition approaches for preventing and improving CF. My main task this year was to verify the reliability and validity of the Memory Complaint Questionnaire in Japanese (MAC-Q-J) through a web-based survey. Additionally, I studied the impact of dietary diversity on the transition from robustness to CF using 14 years of cognitive function and frailty data. I found that high dietary diversity can reduce the progression from robustness to mild cognitive impairment (MCI)/frailty and from frailty to CF in a multi-state model.
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現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
The web survey was successfully conducted to collect useful information for me to verify the reliability and validity of the MAC-Q-J. It provided useful evidence for future use of this questionnaire to assess CF. Based on the existing dietary assessment data and 14 years of cognitive function and frailty data, I was able to secure a certain number of subjects and examine association between dietary diversity and CF development. The findings obtained will be submitted to international academic journals.
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今後の研究の推進方策 |
I will then explore the reliability and validity of the MAC-Q using the data collected from the web survey. Also, the MAC-Q will be used in a new round of the NILS-LSA survey (10th wave) to make a more appropriate determination of participants' CF status. The data will also be further analyzed.
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