| 研究課題/領域番号 |
22KF0062
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| 補助金の研究課題番号 |
21F21356 (2021-2022)
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| 研究種目 |
特別研究員奨励費
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| 配分区分 | 基金 (2023)
補助金 (2021-2022) |
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| 応募区分 | 外国 |
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| 審査区分 |
小区分90110:生体医工学関連
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| 研究機関 | 千葉大学 |
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研究代表者 |
武居 昌宏 千葉大学, 大学院工学研究院, 教授 (90277385)
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| 研究分担者 |
DARMA PANJI 千葉大学, 大学院工学研究院, 外国人特別研究員
DARMA Panji Nursetia 千葉大学, 工学(系)研究科(研究院), 外国人特別研究員
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| 研究期間 (年度) |
2023-03-08 – 2024-03-31
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| 研究課題ステータス |
交付 (2023年度)
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| 配分額 *注記 |
2,300千円 (直接経費: 2,300千円)
2023年度: 1,000千円 (直接経費: 1,000千円)
2022年度: 1,100千円 (直接経費: 1,100千円)
2021年度: 200千円 (直接経費: 200千円)
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| キーワード | gEIT / gEIT Suit / pH-CM / Functional Dyspepsia / Gastric phantom / 3D gastric EIT / Image Reconstruction / Machine Learning |
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| 研究開始時の研究の概要 |
機能性ディスペプシアなど胃疾患を簡単に早期発見できる極低侵襲なウェアラブルセンサは革新的な技術として注目が高い。Darma氏が基盤技術を完成させたml-wEITを、この胃疾患の早期発見技術に展開する。その研究手法はI:機械的かつ電気的に等価な腹部ファントムを作製しml-wE ITを実装し、胃の大きさ、胃酸量、含有流動物量を制御できる腹部ファントムの電気特性を計測する。Ⅱ: ml-wEITを健常者に適用し、空腹時と経口補水液服用時におけるml-wEITによる導電率分布画像をデータベース化する。Ⅲ:ml-wEITの臨床試験研究を行い、胃疾患の患者の電気特性データと導電率分布画像とを取得する。
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| 研究実績の概要 |
This year research achievement are :
(a) Development of pH conversion model Debye-Huckel-Onsager formula has been developed using electrical and mechanical equivalent phantom (b) Gastric Electrical Impedance Tomography Suit (gEIT) suit has been manufactured to measure gastric content volume in healthy Subjects combined with mini-EIT hardware (c) Clinical trial in Chiba University hospital has been performed in 8 healthy subjects.
Published papers: During this year, 3 international Journal has been published PH Conversion Model based on gastric Electrical Impedance Tomography(Sensors Actuators B Chemical Journal), Clinical trial of gEIT(Nature Scientific Report) and Object Oriented Sensitivity Matrix Model (Journal of Electrical Bio Impedance Journal).
Under review papers: During this year 5 papers are still under review, which are:(a) Phase Angle EIT (b) Clustering-Updated Sensitivity matrix for Cell Imaging (c) Multi-node Electrical Impedance Tomography (d) Coupling of Electromagnetic Simulation and Electrical Impedance Tomography (ES-EIT) (e) Hybrid of Electrical Muscle Stimulation and Voluntary Resistance Training by Electrical Impedance Tomography.
Graduated Students under this Project: R.Wicaksono (PhD Student), K. Sakai (Master Student) and Fujimori (Bachelor Student)
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
This year will be planned to implement the stage (３) Integration of gEIT and clinical trial in Chiba
University Hospital. The research plan are:
(a) Fabrication of gEIT suit for human clinical trial in Chiba University Hospital.(b) Accuracy evaluation of gastric content volume visualization between gEIT and Abdomen Ultrasound.(c) Accuracy evaluation of gastic emptying process between gEIT and 13 C Breath Test.
We already finished the plan (a) Fabrication of gEIT suit for human clinical trial in Chiba University Hospital and (b) Accuracy evaluation of gastric content volume visualization between gEIT and Abdomen Ultrasound. the results is published in [1] K. Sakai, P. N. Darma, P. A. Sejati, R. Wicaksono, H. Hayashi, and M. Takei, “Gastric functional monitoring by gastric electrical impedance tomography (gEIT) suit with dual-step fuzzy clustering,” Sci Rep, vol. 13, no. 1, p. 514, 2023. Corresponding Author.
part of the result will be presented in 23rd international conference of Bio Electrical Impedance Tomography (BIO EIT 2023) in Aachen Germany
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| 今後の研究の推進方策 |
Now, we are focussing on (c) Accuracy evaluation of gastic emptying process between gEIT and 13 C Breath Test in collaboration with Chiba University Hospital. Furthermore we will prepare the presentation for 23rd international conference of Bio Electrical Impedance Tomography (BIO EIT 2023) in Aachen Germany from 12th-14th June 2023 and The 4th International Conference and Exhibition on Powder Technology Indonesia in Bali Indonesia from 21-22 August 2023. We will also visit t2i Lab at University of Bergen Norway to talk about research collaboration to combine gastric EIT and Virtual/Augmented Reality. We hope, from the conferences we will obtain meaningful feedback from the experts over the world.We are also preparing JST A-Step proposal in collaboration with Prof. Matsumura and Prof. Hayashi from Chiba University Hospital in order to commercialized the gastric Electrical Impedance Tomography. Furthermore, we are also making a JSPS international proposal in order to propose gastric EIT to solve social problem in indonesia. related with this JSPS international proposal we are trying to collaborate with medical department of gadjah mada university (UGM) Indonesia, we are planning to visit indonesia in August 2023.
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