| 研究開始時の研究の概要 |
Since individual's social class, as well as cognitive function, is not static; as mobility in the social class brings/damages access to useful health resources (insurance, health check), it will generate growing/downcast influence on one’s cognitive ability. To capture the bidirectional dynamic association, the current project utilized longitudinal data in the UK and followed mobility in social class with the relationship on brain structure features and cognitive trajectories over 20 years.
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| 研究実績の概要 |
In the current year, I have successfully completed the project that examining relationship between social status and brain cognitive function. The project involved with data integration on sociodemographic, neuropsychologic and T1W1 images in an open dataset from dementia platform of UK (https://www.dementiasplatform.uk/). The results were published at the Alzheimer's Association International Conference (AAIC), the largest international conference in the field of Alzheimer's disease, and notably selected as lighting presentation. In addition, I finished the collaborative research project with Umea University (Sweden, founded by MIRAI 2.0 Joint Seed). The main results were published in the Annual Meeting of the Gerontology Society of America (DOI: 10.1093/geroni/igac059.2909). This study showed a similar parameter in both countries that lifestyle-disease conditions (diabetes, hypertension, depression, and obesity) explained the relationship between SES and the volume of various limbic lobe regions. Such findings suggest targeting disease management from a professional level (i.e., free medical lectures held by the local community, and easy access to hospitals) is the most actionable and effective strategy for maintaining old adults' cognitive well-being, especially for females facing SES disadvantage.
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