| 配分額 *注記 |
4,680千円 (直接経費: 3,600千円、間接経費: 1,080千円)
2025年度: 910千円 (直接経費: 700千円、間接経費: 210千円)
2024年度: 1,690千円 (直接経費: 1,300千円、間接経費: 390千円)
2023年度: 2,080千円 (直接経費: 1,600千円、間接経費: 480千円)
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| 研究開始時の研究の概要 |
Atopic dermatitis (AD), which is a chronic inflammatory skin disease, manifests as intractable itch. Psychological stress may have a role in the onset or exacerbation of skin disorders such as AD. However, pathophysiologic links between psychological stressors and cutaneous manifestations remain unclear. Therefore, this study focuses on the hypothalamic-pituitary-adrenal axis (HPA) and aims to elucidate the mechanism of exacerbation of the pathogenesis of atopic dermatitis, including itching and dermatitis, and delayed recovery by applying psychological stress to a mouse model of AD.
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