| 研究課題/領域番号 |
23K16301
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| 研究種目 |
若手研究
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| 配分区分 | 基金 |
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| 審査区分 |
小区分58020:衛生学および公衆衛生学分野関連:実験系を含む
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| 研究機関 | 東京大学 |
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研究代表者 |
Wai KyiMar 東京大学, 大学院医学系研究科(医学部), 助教 (10867154)
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| 研究期間 (年度) |
2023-04-01 – 2025-03-31
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| 研究課題ステータス |
交付 (2023年度)
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| 配分額 *注記 |
4,160千円 (直接経費: 3,200千円、間接経費: 960千円)
2024年度: 1,950千円 (直接経費: 1,500千円、間接経費: 450千円)
2023年度: 2,210千円 (直接経費: 1,700千円、間接経費: 510千円)
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| キーワード | Telomere / Positive Deviance / Ageing |
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| 研究開始時の研究の概要 |
Telomere length (TL) has been proposed as a biomarker of biological aging. Positive deviance (PD) concept is idealized for improving public health locally, as the whole community can adopt a healthy lifestyle from healthy peers. It is not possible to clone people; however, it could be possible to understand the unique PD characteristics and have close care on those for socio-behavioral modifications. This study will firstly identify PD characteristics that cope well with premature biological aging, and it would be beneficial to design tailor-made interventions that are applicable in community.
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| 研究実績の概要 |
Telomere length (TL) has been proposed as a biomarker of biological aging. Assuming positive deviants as individuals with a longer TL compared to their peers, I am conducting a community-based cross-sectional study to identify PD characteristics that have the potential to prevent biological aging using the data/biological samples of approximately 1000 participants from the Iwaki health promotion project. The data usage application and the ethical procedure were performed in 2023FY. The questionnaire data and biological sample data were acquired. We will additionally measure the biochemical variables in the urine samples. The protocols and experiment conditions were tested, and trial measurements were performed. The preliminary data analysis of descriptive data was performed.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
3: やや遅れている
理由
There was an unexpected delay in the measurements of variables in urine samples. Due to the change of the affiliation and work location of the principal researcher in the middle of the project, the ethical procedure and material transfer of the samples were performed accordingly to process the data analysis and sample measurements. Thus, the research is slightly behind schedule.
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| 今後の研究の推進方策 |
I plan to perform urine samples analytical measurements, data analysis, and interpretation of results.
I will present the research findings at domestic and international conferences. Moreover, I will prepare the manuscript and publish it in an international peer-reviewed journal.
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