| 研究課題/領域番号 |
23KF0178
|
|---|
| 研究種目 |
特別研究員奨励費
|
| 配分区分 | 基金 |
|---|
| 応募区分 | 外国 |
|---|
| 審査区分 |
小区分42020:獣医学関連
|
|---|
| 研究機関 | 北海道大学 |
|---|
研究代表者 |
中尾 亮 北海道大学, 獣医学研究院, 准教授 (50633955)
|
|---|
| 研究分担者 |
KELAVA SAMUEL 北海道大学, 獣医学研究院, 外国人特別研究員
|
|---|
| 研究期間 (年度) |
2023-11-15 – 2026-03-31
|
| 研究課題ステータス |
交付 (2023年度)
|
| 配分額 *注記 |
2,000千円 (直接経費: 2,000千円)
2025年度: 500千円 (直接経費: 500千円)
2024年度: 1,000千円 (直接経費: 1,000千円)
2023年度: 500千円 (直接経費: 500千円)
|
|---|
| キーワード | Evolution / Genetics / Parasitology / Tick / Transcriptomics / Vector |
|---|
| 研究開始時の研究の概要 |
マダニによって媒介される人や動物の感染症は世界的に問題となっている。気候変動や人間活動により、本来の分布域とは異なる地域にマダニが侵入・定着し、新たな感染症流行をもたらす事例が報告されている。また、同じ種類のマダニでも、病原体を保有するマダニと保有しないマダニが混在しているが、その原因は分かっていない。本研究ではマダニの遺伝子情報を解析することで、マダニの侵入・定着や病原性媒介に関係するマダニの遺伝因子を明らかにする。
|
| 研究実績の概要 |
This project is aimed at uncovering the genetic factors that lead to tick pathogenesis and invasiveness by employing a genomics approach to characterize study tick genotypes and their microbiomes. Sampling of ticks was done in Hokkaido with plans for sampling in other regions of Japan. Moreover, sequence data has been provided by our collaborators in Australia and South Africa. At this time, we are in the preparation of three manuscripts for publication in the upcoming months as a result of this work. These papers encompass topics relating to the phylogeny of ticks from the Rhipicephalus group as well as the systematics of the soft tick family. The scope of this project may expand as more data becomes available through this work and our collaborators.
|
| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
Since my arrival, progress has proceeded as anticipated. The host laboratory has extended a warm welcome and has generously provided ample resources for research endeavors, catering to both my immediate interests and avenues for exploring new fields. There has been time to work on both ongoing research and to investigate and develop new potential research directions. Collaboration with researchers from other countries has been beneficial and many new manuscripts may be published in the near future with this co-operation. Current manuscripts in preparation are proceeding at an acceptable pace with most data analysis complete or in near completion and writing in progress. Productive planning of upcoming research projects to potentially expand on current research ideas.
|
| 今後の研究の推進方策 |
Our ongoing project involves the collection of ticks from diverse regions in Japan and abroad, including Australia. We gather specimens from field surveys in Japan and utilize available samples from Australian museum collections. We conduct genome sequencing of ticks obtained from Japan and a database of ticks housed in Australian museums. This approach aims to identify tick species, tick-borne pathogens, and microbiome. Our upcoming plans include initiating vector competence assessments of Japanese ticks for medically significant viruses prevalent in Japan. We aim to identify the most competent transmission vectors among ticks, informing potential strategies for disease control.
|
