| 研究課題/領域番号 |
25K21569
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| 研究種目 |
若手研究
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| 配分区分 | 基金 |
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| 審査区分 |
小区分90120:生体材料学関連
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| 研究機関 | 北海道大学 |
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研究代表者 |
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| 研究期間 (年度) |
2025-04-01 – 2027-03-31
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| 研究課題ステータス |
交付 (2025年度)
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| 配分額 *注記 |
4,810千円 (直接経費: 3,700千円、間接経費: 1,110千円)
2026年度: 1,820千円 (直接経費: 1,400千円、間接経費: 420千円)
2025年度: 2,990千円 (直接経費: 2,300千円、間接経費: 690千円)
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| キーワード | Nanothermometer / Nanoparticle / Nanoendoscopy / Hyperthermia / Tumor |
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| 研究開始時の研究の概要 |
Localized hyperthermia via heat-generating nanoparticles is a promising approach to cancer therapy. However, its clinical potential is limited as there is a serious lack of standard temperature monitoring techniques with adequate resolution to probe nanoscale temperature changes. To address this challenge, we developed a nanothermometer endoscope based on luminescent lanthanide-doped nanoparticles decorated silver nanowires. The proposed method will allow for better clinical characterization, facilitating clinical translation and commercialization of nanoparticle-based thermal therapies.
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