公募研究
新学術領域研究(研究領域提案型)
We have made great progress on this project. Using viral mediated circuit mapping, activity dependent cellular labeling, behavior and in vivo optogenetics and electrophysiology we have collected a comprehensive data set on the function of the SuM to hippocampal circuits. Our findings demonstrate the SuM can signal environmental novelty to the hippocampus. Unique about this signal is that the SuM can segregate and selectively route different types of information to the dentate gyrus (DG; context novelty) and CA2 (social novelty) for the modulation of mnemonic processing. This content-specific routing of novelty signals represents a new type of modulation of hippocampal processing. A manuscript detailing this findings is currently under peer review. In parallel we have used the efforts of this grant to help our published work demonstrating the application of up-conversion nanoparticles (UCNPs) as a method for minimally-invasive optogenetics (Chen et al, Science 2018).
平成30年度が最終年度であるため、記入しない。
すべて 2018 2017
すべて 雑誌論文 (1件) (うち国際共著 1件、 査読あり 1件、 オープンアクセス 1件) 学会発表 (3件) (うち国際学会 2件、 招待講演 1件)
Science
巻: 359 号: 6376 ページ: 679-684
10.1126/science.aaq1144
