生命現象をつかさどる階層性と不決定性

1992 年度 実績報告書

• 研究課題/領域番号: 04305007
• 研究機関: 名古屋大学
• 研究代表者: 八田 一郎 名古屋大学, 工学部, 教授 (70016070)
• 研究分担者: 清水 博 東京大学, 薬学部, 教授 (30037577) ; 松本 元 電子技術総合研究所, 超分子部, 部長 ; 沢田 康次 東北大学, 電気通信研究所, 教授 (80028133) ; 上田 哲男 名古屋大学大学院, 人間情報学研究科, 教授 (20113524) ; 吉川 研飯 名古屋大学大学院, 人間情報学研究科, 教授 (80110823)
• キーワード: 生命 / 生物 / 生命現象 / 階層性 / 階層構造 / 不決定性 / 決定論 / 生物物理

研究概要

本年度は当初予定した通り研究会1回及び勉強会1回を開くことができた。研究会は平成4年9月7日から9日までグリーンピア南阿蘇で開催された。ここでは代表者及び分担者を中心に階層性を中心とした概念について広く論ずることがでぎ大変有益であった。論じられた問目を列挙すると、人間社会の危機状況における集合的避難、矛盾の証明に見出される進化可能システム、認識における情報の階層性と動的リンキング、ゆらぎ現象の非平衡性と情報の進化等であった。勉強会は平成4年12月25日から26日まで新世代研究所で開催された。ここでは、研究代表者がはじめにこの総合研究の目的について述べ、ついでそれぞれの講師が話をした。特に、生物で現れる階層性について多角的に検討することに力点を置いた。この勉強会での話の題目は、生物過程が伴う不定さーラプラスの悪魔の不在とその後遺症ー、生態学における階層的拡散のモデル脳内リズムの階層性、タンパク質構造の階層性と進化、蛋白質の構造の階層性と機能発現に於ける役割(試論)、及び蛋白質の線形・非線形レーザー分光、であった。このような研究会、勉強会を通じて、階層性という概念が広い分野にわたって使われていることが明かにされ、また生命現象における階層性についての糸口が見いだされつつあることが判った。一方、不決定性については階層性に関する概念を深めて後、もう少し突っ込んで考える必要があることが判った。

研究成果

• [文献書誌] I.Hatta: "Heat capacity measurements with a.c.microcalorimetry" Pure & Appl.Chem.64. 79-86 (1992)
• [文献書誌] H.Yao: "Time-resolved x-ray diffraction and calorimetric strdies at low scan rates II.On the fine structure of the phase transitions in hydrated dipalmitoylphosphatidylethanolamine" Biophys.J.61. 683-693 (1992)
• [文献書誌] H.Takahashi: "Effects of poly(L-lysine) on the structural and thermotropic properties of dipalmitoylphosphatiylglycerol bilayers" Biochim.Biophys.Acta. 1110. 29-36 (1992)
• [文献書誌] I.Hatta: "AC calorimetric study of phase transitions in phosphatidylcholine-cholestrol systems" J.Thermal Analysis. 38. 1775-1783 (1992)
• [文献書誌] 八田 一郎: "生体膜モデル系がとる多形" 表面. 30. 273-280 (1992)
• [文献書誌] M.Yoshimoto: "Coupling among Three Chemical Oscillators:Synchronization,phase-Death and Frustration" Phys.Rev.E.
• [文献書誌] K.Minagawa: "Change of the Higher Order Structure of DNA Induced by the Complexation with Intercalating Synthetic Polymer,as Is Visualized by Fluorescence Microscopy" Nucleic Acids.Res.
• [文献書誌] M.Yoshimoto: "Asymmetric Coupling Stabilizes the Out-of-phase Mode:Experimental Evidence in the Belousov-Zhabotinsky Reaction" Chem.Phys.Lett.189. 18-22 (1992)
• [文献書誌] K.Minagawa: "Dynamical Conformational Change of DNA Induced by Synthetic Polymers:Direct Observation by Fluorescence Microscopy" Nucleic Acids Symp.Ser.27. 69-70 (1992)
• [文献書誌] M.Matsumoto: "Direct Observation of Brownian Motion of Macromolecules by Fluorescence Microscope" J.Polym.Sci.B:Polym.Phys.30. 779-783 (1992)
• [文献書誌] S.Nakata: "Voltage-dependent Capacitance as a Probe for Albumin Adsorption onto a Solid Surface" Biophys.Chem.42. 213-220 (1992)
• [文献書誌] S.Nakata: "New Strategy for Development of a Gas Sensor Based on the Dynamic Characteristics:Principle and Preliminary Experiment" Sensors and Actuators B. 8. 187-189 (1992)
• [文献書誌] S.Nakata: "Entrainment in an Electrochemical Forced Oscillator as a Method of Classification of Chemical Species-a New Strategy to Develop a Chemical Sensor" Physica D. 59. 169-176 (1992)
• [文献書誌] S.Nakata: "Novel Strategy to Develop Chemical Sensors Based on Nonlinear Dynamics-Intelligent Gas Sensor" Sensors and Materials. 4. 101-110 (1992)
• [文献書誌] K.Yoshikawa: "New Strategy of Informational Processing:Utilization of Nonlinear Dynamics to Chemical Sensing" Physica A. 188. 243-250 (1992)
• [文献書誌] K.Yoshkawa: "Opposite Effect between Intercalator and Minor Groove binding Drug on the Higher Order Structure of DNA as Is Visualized by Fluorescence Microscopy" Biochem.Biophys.Res.Commun.188. 1274-1279 (1992)
• [文献書誌] 南川 慶二: "DNA分子のダイナミックスの直接観察" 化学. 47. 562-563 (1992)
• [文献書誌] 松沢 有希子: "DNA分子の直接観察によるゲル電気泳動のパラメータ最適化の試み" 電気泳動最前線クロマトグラフィー最前線. 12. 1-8 (1992)
• [文献書誌] H.Sakurada: "Use pf dihydrorhodamine 123 for detecting intracellulargeneration of peroxides upon UV irradiation in epithelial keratinocytes" Arch.Dermatol.284. 114-116 (1992)
• [文献書誌] C.Yasui: "Adenylate cyclase induces intracellular calcium increase in single human epideramal keratinocytes measured by fluorescence microscopy using Fura 2-AM" British J.Dermatol. 127. 589-594 (1992)
• [文献書誌] T.Ueda: "Pattern dynamics in cellular perception" Phase Transitions. (1993)
• [文献書誌] 沢田 康次: "自然法則と情報処理" 電子情報通信学会誌. 75. 344-349 (1992)
• [文献書誌] Y.Kondo: "Functional Abilities of a Stochastic Logic Neural Network" IEEE TRANSACTIONS ON NEURAL NETWORKS. 3. 434-443 (1992)
• [文献書誌] M.Sato: "Patterning in Hydra Cell Aggregates without the Sorting of Cells from Different Axial Origins" DEVELOPMENTAL BIOLOGY. 151. 111-116 (1992)
• [文献書誌] C.Sato: "Primary Structure of Squid Sodium Channel deduced from the Complementary DNA Sequense" Biochem.Biophys.Res.Commun.186. 61-68 (1992)
• [文献書誌] C.Sato: "Proposed Tertiary Structure of the Sodium Channel" Biochem.Biophys.Res.Commun.186. 1158-1167 (1992)
• [文献書誌] I.Iijima: "Synaptic Activation of Rat Adrenal Medulla examined with a Large Photodiode Array in combination with a Voltage Sensitive Dye" Neuroscience. 51. 211-219 (1992)
• [文献書誌] K.Natsume: "Development of spatio-temporal pattern of Ca^<2+> on the chemotatic behavior of physarum plasmadium" Protoplasma. 166. 55-60 (1992)
• [文献書誌] K.Kobatake: "Control of feeding rhythm in the terrestrial slug lncilaria bilineata" Neuroscience Research. 13. 257-265 (1992)
• [文献書誌] Y.Yamaguchi: "Pattern Recognition with Figure-Ground Separation by Gemeration of Coherent Oscillations" Newral Networks.
• [文献書誌] K.Natsume: "Information processing for the chemotaxis of Phywarum polycephalum by the self-organization of a spatio-temporal pattern of Ca^<2+> concentration" Proc.Int.Symp.on Advance Computing for Life-Science. 253-255 (1992)
• [文献書誌] K.Kimura: "A Self-Organizing Model of Valking Patterns of Insects" Biological Cybernetics.
• [文献書誌] Y.Miyake: "Environment-dependent self-organization of positional information in couplednonlinear oscillator systems" IEICE Trans.Fundamentals.
• [文献書誌] Masuo Suzuki: "General Theory of Higher-Order Decomposition of Exponential Operators and Symplectic Integrotors" Physics Letter A. 165. 387-395 (1992)
• [文献書誌] A.Lipowski: "Convergence of Mean-Field Approximations in Site Percolation and Application of CAM to D=1 Further Neiqhbours Percolation Problem" Journal of Statistical Physics. 69. 1-16 (1992)
• [文献書誌] Masuo Suzuki: "General Nonsymmetric Higher-Order Decomposition of Exponential Operators and Symplectic Integrators" Journal of The Physical Society of Japan. 61. 3015-3019 (1992)
• [文献書誌] A.Lipowski: "Study of Phase Transitions of Antiferromagnetic Ising Models Using the Coherent-Anomaly Method" Journal of The Physical Society of Japan. 61. 2484-2490 (1992)
• [文献書誌] T.Momoi: "Ground-State Properties and Phase Diagram of the Quantum XXZ Antiferromagnet on a Triangular Lattice" Journal of The Physical Society of Japan. 61. 3732-3744 (1992)
• [文献書誌] H.Suzuki: "Convective Instability and Electric Potential Oscillation in a Water-Oil-Water System" Biophysical Chemistry. 45. 153-159 (1992)
• [文献書誌] T.Kawakubo: "Excitation in an Artificial Membrane" The 4th International Symposium on Bioelectronic and Molecular Electronic Devices:Extended Abstracts. 52-53 (1992)
• [文献書誌] N.Ishibashi: "Two-Dimensional Bernstein-Green-Kruskal Solution" J.Phys.Soc.Japan. 61. 2795-2804 (1992)
• [文献書誌] K.Kitahara: "Path Integral Representaeion of Thermodynamic Fluctuations in Non-Equilibrium States" Proc.of Int.Conf.on Path Integrals in Physics(World Scientific). (1993)
• [文献書誌] A.Takamatsu: "Ca^<2+> Effect on Protoplasmic Streaming in Nitella Internodal Cell" Biophysical Journal. 64. 182-186 (1993)
• [文献書誌] T.Musha: "l/f Fluctuations of Phonon Energy in Water" Jap.J.Appl.Phys.31. L370-L375 (1992)
• [文献書誌] B.He: "Equivalent dipole estimations of spontaneous EEG alpha activity:two-dipole approach" Medical & Biological Engr.Computing. 324-332 (1992)
• [文献書誌] 武者 利光: "SSBモデルによる双極子追跡法" 脳と精神の医学. 3. 523-528 (1992)
• [文献書誌] Y.Kuramoto: "Newral Network Model Carrying Phase Information with Application to Collective Dynamics" Progress of Theoretical Physics. 87. 1119-1126 (1992)
• [文献書誌] N.Nakagawa: "Collective Chaos in a Population of Globally Coupled Oscillators" Progress of Theoretical Physics.
• [文献書誌] T.Chawanya: "A Model for Feature Linking via Collective Oscillations in the Primary Visual Cortex" Biological Cybernetics.
• [文献書誌] J.W-I.Lin: "Extremely Weak Linear Electron-Phono Coupling in Iron-Free Hemeproteins Studied by Phase-Modulated Photon Echo." Physical Review. B44. 7356-7361 (1991)
• [文献書誌] S.Kurita: "Structural Dynamics of Proteins Investigated by Hole-Burning Spectroscopy." Journal of Luminescence. 53. 255-258 (1992)
• [文献書誌] Y.Kanematsu: "Resonance Fluorescence Spectra of Dye-Doped Polymers." Journal of Luminescence. 53. 235-238 (1992)
• [文献書誌] T.Kushida: "Spectral Characteristics and Hole Burning in Myoglobin" Molecular Crystals and Liquid Crystals. 217. 171-176 (1992)
• [文献書誌] T.Kushida: "Site-selective Spectroscopy of Myoglobin." SPIE.
• [文献書誌] M Trivelsky: "Phase-slip dynamics in one-dimensional distributed systems" Physical Review A. 45. 4175-4177 (1992)
• [文献書誌] S.Kai: "Transient bimodality in T1-T2 transition in electrohydrodynamic convection in NLC" Physical Review A.
• [文献書誌] S.Nasuno: "Secondary instabilities in electrohydro-convect in nematic liquid crystals" Physical Review A. 46. 4954-4962 (1992)
• [文献書誌] 甲斐 昌一: "電気流体力学的不安定性における乱流I-乱流II転移と欠陥乱流" 流体力学学会誌「ながれ」. 11. 150-156 (1992)
• [文献書誌] S.Kai: "Anomalous Biophoton Emission during Germination Process of Red Bean" Jpn.J.Appl.Phys.
• [文献書誌] 西藤 聖二: "睡眠脳波リズムにおける位相・振幅のダイナミックス" 九州大学工学部集報. 62.2. 121-127 (1992)
• [文献書誌] 西藤 聖二: "光刺激によって引き込みを起こしたα波の位相ダイナミックス" 電子情報通信学会論文誌. J75A.3. 633-639 (1992)
• [文献書誌] 西藤 聖二: "脳波の相関次元" 電子情報通信学会論文誌. J75A.6. 1045-1053 (1992)
• [文献書誌] 八田 一郎: "第4版実験産学構座第4巻熱・圧力" 丸善株式会社, 534(117-125) (1992)
• [文献書誌] 吉川 研一: "非線形科学ー分子集合体のリズムとかたち" 学会出版センター, 177 (1992)
• [文献書誌] T.Ueda: "Oscillations and Morphogenesis" ed.L.Rensing,& Marcel Dekker, 35 (1992)
• [文献書誌] T.Ueda: "Physics of Living State:Dynamics of Information and Fluctuation in Biological Systems" ed.K.Sawada,et al., (1993)
• [文献書誌] 上田 哲男: "生命現象と物理学" 北原 和夫,田中 豊一編, (1993)
• [文献書誌] T.Ueda: "New Functionality Materials" ed.T.Tsuruta,et al., (1993)
• [文献書誌] 清水 博: "生命と場所ー意味を創出する関係科学" NTT出版, 319 (1992)
• [文献書誌] 清水 博: "数理科学No.344特集/バイオコンピュータへの道ホロンコンピュータ" サイエンス社, 8 (1992)
• [文献書誌] 鈴木 増雄 他4名: "物理学最前線29ー相転移の超有効場理とコヒーレント異常法" 共立出版, 215 (1992)
• [文献書誌] 鈴木 増雄 他2名: "岩波講座現代の物理学12経路積分の方法" 岩波書店, 214 (1992)
• [文献書誌] 北原 和夫: "ゆらぎの科学3" 森北出版、武者利光(編), (1993)
• [文献書誌] S.Kai: "Pattern Formation in Complex Dissipative Systems" World Sci.Publishers, 596 (1992)