2001 年度実績報告書

酸素活性種の分子論と反応制御に関する研究の総括

研究課題

研究課題/領域番号	11228204
研究機関	大阪大学
研究代表者	福住俊一大阪大学, 大学院・工学研究科, 教授 (40144430)
研究分担者	諸岡良彦常磐大学, コミュニティー振興学部, 教授 (70016731)
キーワード	酵素反応 / 環境対応 / 触媒・化学プロセス / 生体内分子論 / 錯体化学 / 光エネルギー変換 / 酸素活性種 / 反応制御
研究概要	本研究領域は、様々な酸素活性種の構造と反応性を分子レベルで明らかにし、その反応性を制御する方法を確立することにより、水を電子源とするクリーンな光エネルギー変換を達成するとともに、酸素活性種による新しい高効率かつ高選択的な物質変換手法を開発し、さらに酸素活性種の生体内分子論を解明して、その臨床応用に関する展望を見いだすことを目的としている。研究計画に基づき、「酸素活性種の分子論と反応制御」に関する研究を総合的に推進した。特に、各研究グループ間の協力体制を強化するため、情報交換や装置の共同利用を頻繁に行った。その共同研究の成果は着実に出てきている(研究発表参照)。グループ全体としての研究成果報告および研究打ち合わせについては、平成13年秋に研究代表者の増田秀樹が開催した第34回酸化反応討論会の前日(10月31日)に全体会議を開催した。諸岡は、錯体化学的および触媒化学的な両者の視点から、各研究グループの研究成果を総合的に評価し、今後の研究展開に関する助言を行った。また、福住は、領域代表者として、研究全体の展開に配慮しながら、効率的な研究の展開を図った。

研究成果

(29件)

すべてその他

すべて文献書誌 (29件)

[文献書誌] Shunichi Fukuzumi et al.: "Fine Tuning of the Interaction between the Copper(I) and Disulfide Bond. Formation of a Bis(m-thiolato)dicopper(II) Complex by Reductive Cleavage of the Disulfide Bond with Copper(I)"J.Am.Chem.Soc.. 123・17. 4087-4088 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "C-H Bond Activation of External Substrates with a Bis(m-oxo)dicopper(III) Complex"J.Am.Chem.Soc.. 123・25. 6203-6204 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Charge Separation in a Novel Artificial Photosynthetic Reaction Center Lives 380ms"J.Am.Chem.Soc.. 123・27. 6617-6628 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Oxygenation of Phenols to Catechols by A (μ-η^2:η^2-peroxo)dicopper(II) Complex : Mechanistic Insight into the Phenolase Activity of Tyrosinase"J.Am.Chem.Soc.. 123・27. 6708-6709 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Change in Spin State and Enhancement of Redox Reactivity of Photoexcited States of Aromatic Carbonyl Compounds by Complexation with Metal Ion Salts Acting as Lewis Acids. Lewis Acid-Catalyzed Photoaddition of Benzyltrimethylsilane and Tetramethyltin via Photoinduced Electron Transfer"J.Am.Chem.Soc.. 123・32. 7756-7766 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Photoalkylation of 1O-Alkylacridinium Ion via a Charge-Shift Type of Photoinduced Electron Transfer Controlled by Solvent Polarity"J.Am.Chem.Soc.. 123・35. 8459-8467 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Metal Ion-Catalyzed Cycloaddition vs Hydride Transfer Reactions of NADH Analogues with p-Benzoquinones"J.Am.Chem.Soc.. 123・42. 10191-10199 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Photochemical and Electrochemical Properties of Zinc Chlorin-C_<60>, Dyad as Compared to Corresponding Free-Base Chlorin-C_<60>, Free-Base Porphyrin-C_<60> and Zinc Porphyrin-C_<60> Dyads"J.Am.Chem.Soc.. 123・43. 10676-10683 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Formation, Characterization, and Reactivity of Bis(μ-oxo)dinickel(III) Complexes Supported by A series of Bis[2-(2-pyridyl)ethyl]amine Ligands"J.Am.Chem.Soc.. 123・45. 11168-11178 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Extremely Slow Long-Range Electron Transfer Reactions across Zeolite-Solution Interface"J.Am.Chem.Soc.. 123・45. 11331-11332 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Scandium Ion-Promoted Photoinduced Electron-Transfer Oxidation of Fullerenes and Derivatives by p-Chloranil and p-Benzoquinone"J.Am.Chem.Soc.. 123・50. 12458-12465 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "Large Photocurrent Generation of Gold Eelectrodes Modified with [60]Fullerene-Linked Oligothiophenes Bearing a Tripodal Rigid Anchor"J.Am.Chem.Soc.. 124・4. 532-533 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "OXo-transfer Reaction from A Bis(μ-oxo)dicopper(III) Complex"J.Am.Chem.Soc.. 124・6. 998-1002 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "Efficient Catalysis of Rare-Earth Metal Ions in Photoinduced Electron-Transfer Oxidation of Benzyl Alcohols by a Flavin Analogue"J.Phys.Chem.A. 105・46. 10501-10510 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Electron Transfer Properties of Singlet Oxygen and Promoting Effects of Scandium Ion"J.Phys.Chem.A. 106・7. 1241-1247 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "Dehydrogenation vs Oxygenation in Photosensitized Oxidation of 9-Substituted 10-Methyl-9,10-dihydroacridine in the Presence of Scandium Ion"J.Phys.Chem.A. 106・7. 1465-1472 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "Characterization of Imidazolate-Bridged Dinuclear and Mononuclear Hydroperoxo Complexes"Inorg.Chem.. 40・13. 3200-3207 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Modulation of Coordination Chemistry in Copper(I) Complexes Supported by Bis[2-(2-pyridyl)ethyl]amine-Based Tridentate Ligands"Inorg.Chem.. 40・26. 6604-6609 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Spectroscopy and Photocurrent Generation in Nanostructured Thin Films of Porphyrin-Fullerene Dyad Clusters"Chem.Lett. 784-785 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Quantitative Evaluation of Lewis Acidity of Zinc Ion with Tetradentate Tripodal Ligands in Formation of the Superoxide Complexes"Chem.Lett. 920-921 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Evaluation of Lewis Acidity of Organotin Compounds and the Catalytic Reactivity in Electron Transfer"Chem.Lett. 978-979 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Superoxide Anion Generation via Electron-Transfer Oxidation of Catechin Dianion by Molecular Oxygen in an Aprotic Medium"Chem.Lett. 1152-1153 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Coordination of Semiquinone and Superoxide Radical Anions to the Zinc Ion in SOD Model Complexes that Act as the Key Step in Disproportionation of the Radical Anions"Chem.Eur.J.. 7・22. 4947-4953 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Concentration Effects of Porphyrin Monolayers on the Structure and Photoelectrochemical Properties of Mixed Self-Assembled Monolayers of Porphyrin and Alkanethiol on Gold Electrodes"Langmuir. 17・16. 4925-4931 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Porphyrin Monolayer-Modified Gold Clusters as Photoactive Materials"Adv.Mater. 13・15. 1197-1199 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Charge-transfer emission of compact porphyrin-fullerene dyad analyzed by Marcus theory of electron-transfer"Spectrochim.Acta Part A. 57. 2229-2244 (2001)
[文献書誌] Shunichi Fukuzumi et al.: "Evidence that gold(III) porphyrins are not electrochemically inert : facile generation of gold(II) 5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)porphyrin"Chem.Commun.. 356-357 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "Thermal Intramolecular Electron Transfer in a Ferrocene-Naphthoquinone Linked Dyad Promoted by Metal Ion"Angew.Chem.Int.Ed.. 41・4. 620-622 (2002)
[文献書誌] Shunichi Fukuzumi et al.: "Fullerenes 2001--Volume 11. (Proceedings of the Eighth International Symposium of the 197th Meeting of The Electrochemical Society)"The Electrochemical Society, INC. 69 (2001)

2001 年度 実績報告書

酸素活性種の分子論と反応制御に関する研究の総括

研究代表者

福住 俊一 大阪大学, 大学院・工学研究科, 教授 (40144430)

研究成果

[文献書誌] Shunichi Fukuzumi et al.: "Fine Tuning of the Interaction between the Copper(I) and Disulfide Bond. Formation of a Bis(m-thiolato)dicopper(II) Complex by Reductive Cleavage of the Disulfide Bond with Copper(I)"J.Am.Chem.Soc.. 123・17. 4087-4088 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "C-H Bond Activation of External Substrates with a Bis(m-oxo)dicopper(III) Complex"J.Am.Chem.Soc.. 123・25. 6203-6204 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Charge Separation in a Novel Artificial Photosynthetic Reaction Center Lives 380ms"J.Am.Chem.Soc.. 123・27. 6617-6628 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Oxygenation of Phenols to Catechols by A (μ-η^2:η^2-peroxo)dicopper(II) Complex : Mechanistic Insight into the Phenolase Activity of Tyrosinase"J.Am.Chem.Soc.. 123・27. 6708-6709 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Photoalkylation of 1O-Alkylacridinium Ion via a Charge-Shift Type of Photoinduced Electron Transfer Controlled by Solvent Polarity"J.Am.Chem.Soc.. 123・35. 8459-8467 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Metal Ion-Catalyzed Cycloaddition vs Hydride Transfer Reactions of NADH Analogues with p-Benzoquinones"J.Am.Chem.Soc.. 123・42. 10191-10199 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Photochemical and Electrochemical Properties of Zinc Chlorin-C_<60>, Dyad as Compared to Corresponding Free-Base Chlorin-C_<60>, Free-Base Porphyrin-C_<60> and Zinc Porphyrin-C_<60> Dyads"J.Am.Chem.Soc.. 123・43. 10676-10683 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Formation, Characterization, and Reactivity of Bis(μ-oxo)dinickel(III) Complexes Supported by A series of Bis[2-(2-pyridyl)ethyl]amine Ligands"J.Am.Chem.Soc.. 123・45. 11168-11178 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Extremely Slow Long-Range Electron Transfer Reactions across Zeolite-Solution Interface"J.Am.Chem.Soc.. 123・45. 11331-11332 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Scandium Ion-Promoted Photoinduced Electron-Transfer Oxidation of Fullerenes and Derivatives by p-Chloranil and p-Benzoquinone"J.Am.Chem.Soc.. 123・50. 12458-12465 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "Large Photocurrent Generation of Gold Eelectrodes Modified with [60]Fullerene-Linked Oligothiophenes Bearing a Tripodal Rigid Anchor"J.Am.Chem.Soc.. 124・4. 532-533 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "OXo-transfer Reaction from A Bis(μ-oxo)dicopper(III) Complex"J.Am.Chem.Soc.. 124・6. 998-1002 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "Efficient Catalysis of Rare-Earth Metal Ions in Photoinduced Electron-Transfer Oxidation of Benzyl Alcohols by a Flavin Analogue"J.Phys.Chem.A. 105・46. 10501-10510 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Electron Transfer Properties of Singlet Oxygen and Promoting Effects of Scandium Ion"J.Phys.Chem.A. 106・7. 1241-1247 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "Dehydrogenation vs Oxygenation in Photosensitized Oxidation of 9-Substituted 10-Methyl-9,10-dihydroacridine in the Presence of Scandium Ion"J.Phys.Chem.A. 106・7. 1465-1472 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "Characterization of Imidazolate-Bridged Dinuclear and Mononuclear Hydroperoxo Complexes"Inorg.Chem.. 40・13. 3200-3207 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Modulation of Coordination Chemistry in Copper(I) Complexes Supported by Bis[2-(2-pyridyl)ethyl]amine-Based Tridentate Ligands"Inorg.Chem.. 40・26. 6604-6609 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Spectroscopy and Photocurrent Generation in Nanostructured Thin Films of Porphyrin-Fullerene Dyad Clusters"Chem.Lett. 784-785 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Quantitative Evaluation of Lewis Acidity of Zinc Ion with Tetradentate Tripodal Ligands in Formation of the Superoxide Complexes"Chem.Lett. 920-921 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Evaluation of Lewis Acidity of Organotin Compounds and the Catalytic Reactivity in Electron Transfer"Chem.Lett. 978-979 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Superoxide Anion Generation via Electron-Transfer Oxidation of Catechin Dianion by Molecular Oxygen in an Aprotic Medium"Chem.Lett. 1152-1153 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Coordination of Semiquinone and Superoxide Radical Anions to the Zinc Ion in SOD Model Complexes that Act as the Key Step in Disproportionation of the Radical Anions"Chem.Eur.J.. 7・22. 4947-4953 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Concentration Effects of Porphyrin Monolayers on the Structure and Photoelectrochemical Properties of Mixed Self-Assembled Monolayers of Porphyrin and Alkanethiol on Gold Electrodes"Langmuir. 17・16. 4925-4931 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Porphyrin Monolayer-Modified Gold Clusters as Photoactive Materials"Adv.Mater. 13・15. 1197-1199 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Charge-transfer emission of compact porphyrin-fullerene dyad analyzed by Marcus theory of electron-transfer"Spectrochim.Acta Part A. 57. 2229-2244 (2001)

[文献書誌] Shunichi Fukuzumi et al.: "Evidence that gold(III) porphyrins are not electrochemically inert : facile generation of gold(II) 5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)porphyrin"Chem.Commun.. 356-357 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "Thermal Intramolecular Electron Transfer in a Ferrocene-Naphthoquinone Linked Dyad Promoted by Metal Ion"Angew.Chem.Int.Ed.. 41・4. 620-622 (2002)

[文献書誌] Shunichi Fukuzumi et al.: "Fullerenes 2001--Volume 11. (Proceedings of the Eighth International Symposium of the 197th Meeting of The Electrochemical Society)"The Electrochemical Society, INC. 69 (2001)

2001 年度実績報告書

福住俊一大阪大学, 大学院・工学研究科, 教授 (40144430)