| 研究実績の概要 |
In this project, we aim to understand how neofunctionalization and subfunctionalization occur and whether they are driven by particular genetic elements or functions of nearby genes after genome polyploidization. Following the identification and characterization of genome polyploidization in newly sequenced fungal genomes, we investigated evolution rates among orthologs and paralogs, transcriptional orientation of newly formed adjacent genes, and conservations of stoichiometry for protein complexes and biological pathway components. Specifically, improved gene ontology annotation achieved during the last year allowed us to identify the relationship between genes in newly formed gene clusters. In the next year, we will look for sequence motifs in nearby untranslated regions that might be related to these conserved rearrangements.
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