| 研究課題/領域番号 |
14J00541
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| 研究機関 | 大阪大学 |
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研究代表者 |
尹 熙晶 大阪大学, 工学研究科, 特別研究員(DC2)
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| 研究期間 (年度) |
2014-04-25 – 2016-03-31
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| キーワード | Metal-Oxo Complexes / Enzyme Model / Lewis Acid Effect / Hydride Transfer / Electron Transfer |
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| 研究実績の概要 |
During 2014 research, extended work of Mn(IV)-oxo complexes has been mainly focused. The published result is ‘the mechanism of hydride transfer from NADH analogues to an nonheme Mn(IV)-oxo complex’ on Chemical Communication in 2014. Mn(IV)-oxo complex is compared with that of hydride transfer to an Fe(IV)-oxo complex revealing the reaction proceeds via a rate-determining electron transfer with no deuterium kinetic isotope effect. Therefore, a charge-transfer complex formed between the Mn(IV)-oxo complex and NADH analogues is clarified in the hydride transfer reaction. Also, The factors that tune the redox reactivity of the oxo intermediates were thoroughly investigated especially with the effects of proton. Diprotonated nonheme Mn(IV)-oxo complexes, [(L)MnIV(O)]2+－(HOTf)2, were synthesized by adding HOTf and were characterized by various spectroscopic methods. The fundamental electron-transfer properties of [(L)MnIV(O)]2+－(HOTf)2 have also been investigated to compare the reactivities with OAT and HAT reactions.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
I have been carrying on multiple projects, of course, some of them resulted with published papers and some of them is not. First of all, I have successfully summarized my work on Hydride Transfer by Manganese(IV)-oxo complexes and it appeared on RSC Chemical Communications. In addition, Proton effect on Manganese(IV)-oxo complexes was a bit complicated, but recently it was accepted at RSC Chemical Science. I am proud of such a result for a year and hope that it will be continuously studied for next another year.
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| 今後の研究の推進方策 |
Currently i have on going research on Lewis acid effect on Manganese(IV)-oxo complexes combining with water effect for that matter. So far, interesting key data has been obtained and i am certain that it will be successfully finished. In addition, I have found very interesting data on photo-irradiated metal complexes. It seems challenging but i am happy to be the pioneer of researching of very undiscovered area.
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