| 研究課題/領域番号 |
16F16340
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| 研究機関 | 京都大学 |
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研究代表者 |
村上 正浩 京都大学, 工学研究科, 教授 (20174279)
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| 研究分担者 |
ZHOU WANG 京都大学, 工学研究科, 外国人特別研究員
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| 研究期間 (年度) |
2016-10-07 – 2019-03-31
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| キーワード | photo redox / copper catalyst / リグニンモデルの分解 |
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| 研究実績の概要 |
In the past half year, we developed a photo redox and copper catalytic system for C-C bond cleavage of β-O-4 lignin model compound, giving 3,4-dimethoxybenzaldehyde and 2-methoxyphenyl formate as products in moderate yields. A series of substrates with β-O-4 and β-1 linkage were well-tolerated under standard conditions. The reaction could take place under sunlight, giving the desired products in comparable yields. Some experiments have been carried out to probe the mechanism of this chemistry. Copper catalyst plays an important role in the formation of 2-methoyphenyl formate.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
The research on photo redox and copper catalysis for C-C bond cleavage of lignin model compound have accomplished. We are preparing the manuscript to publish the relevant results. At the same time, we are carrying out a new research topic on photoredox catalyzed C-C bond cleavage of olefin for site-selective alkylation of pyridine.
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| 今後の研究の推進方策 |
For the following fiscal year, we will focus on photoredox catalyzed C-C bond cleavage of olefin for site-selective alkylation of pyridine. We have established the optimal reaction conditions. Now, the substrate scope of this transformation is under investigation. After accomplishing that, we will move to mechanistic study and synthetic application.
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