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2017 年度 実績報告書

生活習慣病の増加に伴う疾病と社会的健康決定要因との逆説的関連性のメカニズム

研究課題

研究課題/領域番号 17F17110
研究機関東京医科歯科大学

研究代表者

中村 桂子  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (00211433)

研究分担者 RAHMAN MD. Mosiur  東京医科歯科大学, 医歯(薬)学総合研究科, 外国人特別研究員
研究期間 (年度) 2017-10-13 – 2020-03-31
キーワードDiabetes / glycemic level / diet / medication / physical exercise / health-related QOL / Bangladesh
研究実績の概要

Studies from developed countries have shown that, probability of developing diabetes was higher among the people belonging to low socioeconomic group. However, there is a dearth of evidence from developing countries on social epidemiology of diabetes. These studies are typically based on local or regional samples or strength of the associations was found to be inconsistent. We are going to expand our work as a large scale epidemiological data analysis considering 25 developing countries to address the association between socioeconomic status (SES) with prevalence, awareness, and control of diabetes. Further, through a field survey, by using multicenter, prospective, longitudinal cohort study design, we attempt to identify the factors associated with barriers to and determinants of poor glycemic control in relation to SES among the diabetics in Bangladesh.
During this period, we have reviewed the scientific literatures, applied for secondary data access to MEASURE DHS authority, and developed survey protocol in collaboration with diabetic centers in Dhaka for our primary data collection. To improving my researching skills, under the supervision of my Professor, I also analyzed the UNICEF MICS data of Lao PDR.

現在までの達成度 (区分)
現在までの達成度 (区分)

2: おおむね順調に進展している

理由

Our research has progressed smoothly. For secondary data analyses, we already have accessed the DHS data from 25 developing countries. We already shortened the variables from the secondary data sources, which are required for our analysis. Now we are in a stage of analyzing these data. For primary data analyses, we already developed our study protocol. We are now in a stage to submit the documents for ethical approval from the Ethical Committee of University of Rajshahi, Bangladesh and Ethical Review Board, Tokyo Medical and Dental University, Japan. We also developed the questionnaires, reviewed the instruments for collection of data, estimated the budget, and the number of interviewers required for our data collection as well as their qualification to carry out the field work. We already contacted to the directors of the diabetic centers in Bangladesh from where we will recruit the participants.

今後の研究の推進方策

For secondary data analyses, we planned to consider hypertension, diabetes, prostate cancer, breast cancer, and cervical cancer as a proxy of noncommunicable disease. We considered the following countries Albania, Armenia, Azerbaijan, Bangladesh, Benin Bolivia Brazil. Burkina Faso. Colombia. Cote d’Ivore, Dominican Republic, Egypt, Guatemala, Honduras, Jordan, Kyrgyz Republic, Lesotho, Namibia, Peru. Philippines, South Africa, Tajikistan, Tanzania, Ukraine ad Uzbekistan. These countries are chosen based on availability of NCDs data in DHS surveys. Currently, we are planning to analyze these data sets, to see whether socioeconomic variation exists in NCDs among those countries.
For primary data analyses, to identifying barriers to and determinants of poor glycemic control, we planned to consider 500 type 2 diabetes patients aged 21 years and older and reporting a diagnosis of diabetes for at least 1 year before their index date from three diabetes centers located in three divisional cities of Bangladesh. We will assess each participant prospectively at 3 and 6 months. We will collect data on glycemic level, health related quality of life, diabetes complications, out of pocket expenses due to care of diabetes, adherence to treatment visit, medication, diet, and physical exercise. Descriptive statistics and multivariate analyses will be used to analyze the data.

  • 研究成果

    (8件)

すべて 2018 2017 その他

すべて 国際共同研究 (2件) 雑誌論文 (6件) (うち国際共著 6件、 査読あり 6件、 オープンアクセス 6件)

  • [国際共同研究] University of Rajshahi/Ministry of Planning(Bangladesh)

    • 国名
      バングラデシュ
    • 外国機関名
      University of Rajshahi/Ministry of Planning
  • [国際共同研究] Hue University Medicine and Pharmacy(ベトナム)

    • 国名
      ベトナム
    • 外国機関名
      Hue University Medicine and Pharmacy
  • [雑誌論文] Maternal high-risk fertility behavior and association with chronic undernutrition among children under age 5 y in India, Bangladesh, and Nepal: Do poor children have a higher risk?2018

    • 著者名/発表者名
      Mosiur Rahman, Syed Emdadul Haque, Md. Sarwar Zahan, Md. Jahirul Islam, Md. Mosfequr Rahman, Md. Asaduzzaman, Md. Nuruzzaman Haque, Ahmed Zohirul Islam, Md. Durul Huda, Md. Golam Mostofa.
    • 雑誌名

      Nutrition

      巻: 49 ページ: 32-40

    • DOI

      10.1016/j.nut.2017.10.001

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Examining the relationship between socioeconomic status and the double burden of maternal over and child under-nutrition in Bangladesh.2018

    • 著者名/発表者名
      Syed Emdadul Hauqe, Kayako Sakisaka, Mosiur Rahman.
    • 雑誌名

      European Journal of Clinical Nutrition

      巻: 72 ページ: 1-10

    • DOI

      10.1038/s41430-018-0162-6

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Assessment of knowledge regarding tuberculosis among industrial labors of Rajshahi District, Bangladesh: a cross- sectional study.2018

    • 著者名/発表者名
      Md. Masud Rana, Md. Rafiqul Islam, Mosiur Rahman, Tunku Kamarul Zaman, Premananda Bharati, Md. Golam Hossain.
    • 雑誌名

      Human Biology Review

      巻: 7 ページ: 1

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Assessing the link between witnessing inter-parental violence and the perpetration of intimate partner violence in Bangladesh.2017

    • 著者名/発表者名
      Md Jahirul Islam, Mosiur Rahman, Lisa Broidy, Syed Emdadul Haque, Yu Mon Saw, Nguyen Huu Chau Duc, Md Nurruzzaman Haque, Md Mostafizur Rahman, Md Rafiqul Islam, Md Golam Mostofa.
    • 雑誌名

      BMC Public Health

      巻: 17 ページ: 183

    • DOI

      10.1186/s12889-017-4067-4

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Association between high-risk fertility behaviours and the likelihood of chronic undernutrition and anaemia among married Bangladeshi women of reproductive age.2017

    • 著者名/発表者名
      Mosiur Rahman, Md Jahirul Islam, Syed Emdadul Haque, Yu Mon Saw, Md Nurruzzaman Haque, Nguyen Huu Chau Duc, Saber Al-Sobaihi, Thu Nandar Saw, Md Golam Mostofa, Md Raqul Islam
    • 雑誌名

      Public Health Nutr

      巻: 20 ページ: 305-314

    • DOI

      10.1017/S136898001600224X

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Association between contraceptive use and socio-demographic factors of young fecund women in Bangladesh.2017

    • 著者名/発表者名
      Ahmed Zohirul Islam, Mosiur Rahman, Md Golam Mostofa.
    • 雑誌名

      Sex Reprod Health

      巻: 13 ページ: 1-7

    • DOI

      10.1016/j.srhc.2017.05.001

    • 査読あり / オープンアクセス / 国際共著

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公開日: 2018-12-17   更新日: 2022-08-19  

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