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2018 年度 実績報告書

生活習慣病の増加に伴う疾病と社会的健康決定要因との逆説的関連性のメカニズム

研究課題

研究課題/領域番号 17F17110
研究機関東京医科歯科大学

研究代表者

中村 桂子  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (00211433)

研究分担者 RAHMAN MD. Mosiur  東京医科歯科大学, 医歯(薬)学総合研究科, 外国人特別研究員
研究期間 (年度) 2017-10-13 – 2020-03-31
キーワードDiabetes / Glycemic level / diet / medication / physical exercise / health-related QOL / Bangladesh
研究実績の概要

To identify the factors associated with barriers to and determinants of poor glycemic control, we have planned to conduct a cohort study in 500 type 2 diabetics aged 21 years and over from three diabetics center, located in three divisional cities in Bangladesh. We analyzed the baseline data of this cohort study. The results of the baseline data indicate that, from the total sample population, 50.2% were male, 33.8% were 21-46 years old, 14.6% had no education, and 80.0% were living in a nuclear family. Approximately 37.0% were living in rural areas and 33.0% were defined as being rich. The results of the analyses indicated that 57.4% of the study participants were not adhering to recommended oral hypoglycemic agents, only 26.0% of reported adhering to dietary recommendations, and adherence to prescribed recommendations for physical activity were 37.8%. Approximately 62.0% of patients reported not performing self-monitoring of blood glucose. A substantial percentage (71.8%) of the patients had poor blood glycemic control (HbA1c<7.0%) and 33.2% of them visited the diabetics center regularly. The result also shows that more than two-fifths of the patients (41.0%) were either overweight or obese. Approximately 44.0% of patients were suffering from hypertension and 42.6% reported to suffer from depression.

現在までの達成度 (区分)
現在までの達成度 (区分)

2: おおむね順調に進展している

理由

Our research has progressed smoothly. During this period from April 2018-March 2019, we developed our study protocol (developed the questionnaires, reviewed the instruments for collection of data, estimated the budget, and the number of interviewers required for our data collection, and submitted our ethical documents to TMDU IRB and Ethical Committee of the Institute of Biological Sciences, University of Rajshahi, Bangladesh). After receiving the ethical approval, we have already collected our baseline data between the period from July 2018 to September 2018. We are now in a stage to analyze the baseline data. Using the baseline data, we already finished the analyses of six of our tentative manuscripts under the following headings: 1) Mediators of the association between low socioeconomic status and poor glycemic control among type 2 diabetic in Bangladesh; 2) Relative contribution of selected risk factors to prevalence and severity of periodontal disease in patients with diabetics in Bangladesh; 3) Identifying perceived barriers to recommended diet, medication, and physical activity adherence in type 2 diabetics: an exploratory factorial analysis; 4) Association of good glycemic control and cost of diabetes care in Bangladesh; 5) The role of perceived barriers in explaining socio-economic status differences in adherence to diet, medication and physical activity guidelines in type 2 diabetics: a mediation study; 6) Assessment of the quality of life through the SF-12 questionnaire in diabetic patients according to prevalence and severity of periodontal disease.

今後の研究の推進方策

1. Conduct end line survey
2. Finalize the manuscript (using the baseline data) for submission to international journals
3. Entry end line data and perform analysis
4. Writing the manuscript using the cohort study data and submit the manuscript to journals

  • 研究成果

    (10件)

すべて 2019 2018 その他

すべて 国際共同研究 (2件) 雑誌論文 (8件) (うち国際共著 8件、 査読あり 8件、 オープンアクセス 8件)

  • [国際共同研究] University of Rajshahi/Dhaka Diabetic Center/Barishal Diabetic Center(バングラデシュ)

    • 国名
      バングラデシュ
    • 外国機関名
      University of Rajshahi/Dhaka Diabetic Center/Barishal Diabetic Center
    • 他の機関数
      1
  • [国際共同研究] Ministry of Health, Lao PDR(ラオス)

    • 国名
      ラオス
    • 外国機関名
      Ministry of Health, Lao PDR
  • [雑誌論文] Examining the relationship between socioeconomic status and the double burden of maternal over and child under-nutrition in Bangladesh.2019

    • 著者名/発表者名
      Syed Emdadul Hauqe, Kayako Sakisaka & Mosiur Rahman
    • 雑誌名

      Eur J Clin Nutr

      巻: 75 ページ: 531-540.

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Secondhand smoke and illness: are mother-child pairs from low socioeconomic strata at 2 increased risk in Bangladesh?2019

    • 著者名/発表者名
      Rahman M, Mostofa MG, Rahman MM, et al.
    • 雑誌名

      Int J Tuberc Lung Dis

      巻: 1 ページ: 1-10

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Maternal pregnancy intention and its association with low birthweight and pregnancy complications in Bangladesh: Findings from a hospital-based study.2019

    • 著者名/発表者名
      Rahman MM, Nasrin SO, Rahman M, et al.
    • 雑誌名

      International Health

      巻: 1 ページ: 1-10

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Second hand smoke, knowledge/attitude and socioeconomic status among married Bangladeshi women: a cross-sectional study.2019

    • 著者名/発表者名
      Rahman M, Hasan SM, Haque SE, et al.
    • 雑誌名

      Sao Paulo Medical Journal

      巻: 1 ページ: 1-10

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Assessing the link between endorsing attitudes justifying partner abuse and reproductive health care utilization among women in Lao PDR2018

    • 著者名/発表者名
      Manivong Dasavanh、Rahman Mosiur、Nakamura Keiko、Seino Kaoruko
    • 雑誌名

      Journal of Rural Medicine

      巻: 13 ページ: 124~133

    • DOI

      https://doi.org/10.2185/jrm.2968

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Socio-economic inequalities in secondhand smoke exposure at home in the context of mother-child pairs in Bangladesh2018

    • 著者名/発表者名
      Rahman M.、Haque M.N.、Rahman M.M.、Mostofa M.G.、Zahan M.S.、Mahmudul Hasan S.M.、Huda M.D.、Ahmed M.K.、Miraz Mahmud H.M.
    • 雑誌名

      Public Health

      巻: 161 ページ: 106~116

    • DOI

      DOI: 10.1016/j.puhe.2018.04.018

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Maternal high-risk fertility behavior and association with chronic undernutrition among children under age 5?y in India, Bangladesh, and Nepal: Do poor children have a higher risk?2018

    • 著者名/発表者名
      Rahman Mosiur、Haque Syed Emdadul、Zahan Sarwar、Islam Jahirul、Rahman Mosfequr、Asaduzzaman M.D.、Haque Nuruzzaman、Islam Ahmed Zohirul、Huda Durul、Mostofa Golam
    • 雑誌名

      Nutrition

      巻: 49 ページ: 32~40

    • DOI

      https://doi.org/10.1016/j.nut.2017.10.001

    • 査読あり / オープンアクセス / 国際共著
  • [雑誌論文] Assessment of knowledge regarding tuberculosis among industrial labors of Rajshahi District, Bangladesh: a cross- sectional study.2018

    • 著者名/発表者名
      Rana, MM, Islam, MR, Rahman, MM, Zaman, TK, Bharati P and Hossain G.
    • 雑誌名

      Human Biology Review

      巻: 7 ページ: 155-171

    • 査読あり / オープンアクセス / 国際共著

URL: 

公開日: 2019-12-27  

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