| 研究課題/領域番号 |
17J00597
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| 研究機関 | 沖縄科学技術大学院大学 |
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研究代表者 |
BEEDESSEE Girish 沖縄科学技術大学院大学, 科学技術研究科, 特別研究員(DC1)
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| 研究期間 (年度) |
2017-04-26 – 2020-03-31
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| キーワード | Dinoflagellates / retrotransposition / metabolites |
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| 研究実績の概要 |
During this year I was able to write a paper that describe the evolutionary history of secondary metabolisms in several dinoflagellates genomes and how such evolution is linked to environmental/ecological settings. I was able to link secondary metabolism pathways to metabolites and how duplication, retrotransposition and horizontal gene transfer led to the expansion of such pathways. Additionally, I am now designing the use of long reads RNA sequencing to understand RNA metabolism in dinoflagellates.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
1: 当初の計画以上に進展している
理由
1. We completed the genome sequencing of Amphidinium gibbosum and combined several omics approach to understand biosynthesis of secondary metabolites.
2. We proposed a model for secondary metabolites biosynthesis in dinoflagellates based on genomics surveys.
3. We generated long reads Isoseq sequencing to help understand transcriptomics in Amphidinium.
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| 今後の研究の推進方策 |
Currently I will employ long read RNA sequencing from Oxford Nanopore so as to study the role of different transcriptomic events such as splicing and polyadenylation. this will be done with help of RNA labeling and machine learning algorith.
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