| 研究課題/領域番号 |
17K09666
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| 研究機関 | 慶應義塾大学 |
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研究代表者 |
ヒガブ中井 アハマド 慶應義塾大学, 医学部(信濃町), 特任講師 (00507915)
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| 研究期間 (年度) |
2017-04-01 – 2020-03-31
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| キーワード | Calorie restriction / Aging |
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| 研究実績の概要 |
We have detected the effect of Calorie restriction on the histology of trachea and lung. We have examined the effect of Calorie restriction on lung stem cells, using the in vitro colony forming assay. We have examined the effect of aging on lung inflammation. We found that aging induced lung inflammation. We discovered that Calorie restriction significantly reduced the aging-induced lung inflammation.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
Our plan worked as expected, and data are proving our original hypothesis.
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| 今後の研究の推進方策 |
We are examining the effect of Calorie restriction on the severity of lung injury. In other words, will the lungs that had been exposed to Calorie restriction be able to resist the injury more than the lung that received standard diet.
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| 次年度使用額が生じた理由 |
This year, some research plans were delayed due to demise of the head of the division. This year, we expect a new head of division coming, and we will undertake the delayed experiments and catch up with the research plan.
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