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2021 年度 実績報告書

早期の肺炎球菌ワクチン導入が鼻咽頭定着の肺炎球菌菌量に与える影響についての検討

研究課題

研究課題/領域番号 17K16272
研究機関長崎大学

研究代表者

ドバデル ビム  長崎大学, 熱帯医学研究所, 准教授 (80761113)

研究期間 (年度) 2017-04-01 – 2022-03-31
キーワードpneumococcus / serotypes / PCV10 / children / Nepal
研究実績の概要

We have successfully enrolled 600 babies and have followed them at the age of 10 weeks (n=585), 14 weeks (n=564), 9 months (n=470), 12 months (n=340), 15 months (n=169). Follow up children at 12 months and 15 months still going on. Till date, 1530 nasopharyngeal samples have been collected. DNA extraction has been started. Material transfer agreement and approval is already taken from Nepal Health Research Council, Kathmandu. DNA will be brought to Nagasaki and will be tested for pneumococcal serotypes, and prevalence of vaccine and non-vaccine serotypes will be determined. Epidemiological and clinical data are being analysed in STATA to estimate the incidence of acute respiratory infections among infants after the introduction of pneumococcal conjugate vaccine in Nepal.

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公開日: 2022-12-28  

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