研究課題/領域番号 |
18F18351
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研究機関 | 東京大学 |
研究代表者 |
J・J Delaunay 東京大学, 大学院工学系研究科(工学部), 准教授 (80376516)
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研究分担者 |
TAI YI-HSIN 東京大学, 工学(系)研究科(研究院), 外国人特別研究員
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研究期間 (年度) |
2018-11-09 – 2021-03-31
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キーワード | particle trapping / Raman spectroscopy |
研究実績の概要 |
Two optical fiber tips, facing each other, are used to trap and detect particles as well as bacteria suspended in a fluidic channel. This fiscal year, the main achievements are threefold: 1) optimization of the shapes of the two fiber tips to achieve enhanced surface Raman spectroscopy near the tip of one of the two fibers, 2) identification of Raman signal that can be used for bacteria discrimination, and 3) particle trapping between the two optical fiber tips by dielectrophoresis that is made possible by the coating of the two fiber tips with transparent and conductive ultra-thin films. The proposed tip fibers have also been used to develop an ultra-sensitive portable refractometer (collaboration with Professor Pei-Kuen Wei, Academia Sinica, Taiwan) with the ability to monitor variation in solutes such as sucrose (published in the journal sensors).
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現在までの達成度 (区分) |
現在までの達成度 (区分)
3: やや遅れている
理由
Using the fabricated optical fiber tips, Surface enhanced Raman spectroscopy and particle trapping have been demonstrated separately. The combination of the two techniques on the same pair of optical fiber tips is difficult. Currently, the Raman signal is too weak to be collected by an optical fiber tip coated with the thin conductive layer that is used for the dielectrophoresis process. Further optimization of the different fabrication processes is required to improve the intensity of the Raman signal and its collection by the fiber tip.
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今後の研究の推進方策 |
Combine the two techniques for excitation/collection of surface-enhanced Raman signal and trapping particles on the same pair of optical fiber tips. Achieve simultaneously particle trapping and their detection/identification by Raman spectroscopy. Specifically, we will attempt detection of the Raman signal of adenine which is thought to be produced by bacteria (ATTC 25922). To demonstrate the validity of the technique, variation in the Raman signal intensity will be recorded as a function of the relative position of the two optical fiber tips and bacteria concentration.
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