| 研究実績の概要 |
The first project:Iridium-Catalyzed Alkene-Selective Transfer Hydrogenation with 1,4-Dioxane as Hydrogen Donor (in manuscript). Herein, an iridium-catalyzed transfer hydrogenation of alkenes using 1,4-dioxane as a hydrogen donor is described. The use of 1,2-bis(dicyclohexylphosphino)ethane (DCyPE), featuring bulky and highly electron-donating properties, exhibited high catalytic activity. This protocol allowed chemoselective transfer hydrogenation of alkenes over other potentially reducible functional groups such as carbonyl, nitro, cyano and imino groups in the same molecules.
The second project: reversible Dehydrogenation and Hydrogenation of N-Heterocycles with a Heterogeneous Bisphosphine-Ir Catalyst (on-going). Herein, we report a novel and efficient heterogeneous bisphosphine-Ir catalyst comprised of our original polystyrene-cross-linking bisphosphine PS-DPPBz and [IrCl(cod)]2 for the acceptorless dehydrogenation of N-heterocycles (Scheme 1). It should be noted that bisphoshine catalyst without ancillary ligand for acceptoless dehydrogantion reactions is rare. Moreover, the reverse process, namely, hydrogenation of unsaturated N-heterocycles proceeded with the same catalyst. Surprisingly, N-substituted heterocycles also underwent acceptorless dehydrogenations without hydrogen acceptors or oxidants, which indicates the reaction mechanism presumably distinct.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
1: 当初の計画以上に進展している
理由
As for the project of acceptorless dehydrogenation, I have expected the reaction can be performed in a large scale and produce large volume hydrogen gas. This may be valuable for the hydrogen fueling car. In the future, the reaction was expected to be performed for flow chemistry.
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