| 研究実績の概要 |
Based on the results of the previous year, we confirmed the mechanism where when the secondheterocyclic ligand in a bi-ligand auro-complex that could tautomerize between thioamide and iminothioimide resulted in the formation of the auro-complex. The year bi-ligand auro-complexes were found to be formed by non-heterocyclic compounds that possessed the ability to tautomerize between thioamide and iminothioimide, urea and methylated ureas. For 1,3-dimethyluea where the 2 symmetric methyl appeared asymmetric suggesting binding between the gold and amine, similar to the parent thiopronin-gold. This year the pyridine bath component,which accelerated deposition was investigated in more depth. Pyridine derivatives had been observed to accelerate gold deposition by undocking the catalytic site occupied by the ligand 2, which inhibited the oxidation of ascorbate.The mechanism of the Pyridine acceleration effect was also further investigated. Aqueous soluble pyridine derivatives, nicotinic acid, pyridine-3-sulphonic acid,niccotinimide, BN-benzyl pyridine-3-sulphonic acid all showed accelerating effects based on the molar concentration.
In another experiment, Thionicotinamide possessesing both the thioamide and pyridine moieties accelerated the bath enough for deposition but the reaction was slower than other complexes and not as uniform.The first discovered AMT and MTZ complexes remain the most reactive and give best results.
Finally a study was performed on the cell sheet detachment characteristic from MTZ, AMZ and AMT.Superior detachment form the more conductive AMT film occurred..
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