| 研究実績の概要 |
I previous year we have preformed filtering and data annotation. We used several bioinformatic tools to establish pipeline for gene set analysis. We have annotated variants to genes and used genes to analyze affected gene sets. Validation of variants showed us relatively high true positive rate. Our data analysis pipeline performed satisfactory and we did not experienced major problems. We have used pipeline to analyze data and the analysis was satisfactory. We established that exome sequecing is valuable tool to analyze genetic predisposition to psychiatric disorders, and can be use to understand the underlying molecular mechanism of disease
|
