研究課題/領域番号 |
18K09469
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研究機関 | 国立研究開発法人産業技術総合研究所 |
研究代表者 |
Ding Wuxiao 国立研究開発法人産業技術総合研究所, 材料・化学領域, 主任研究員 (90598757)
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研究期間 (年度) |
2018-04-01 – 2021-03-31
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キーワード | Melamine NanoTube / Melamine NanoParticle / 5-FU |
研究実績の概要 |
I have prepared Melamine NanoTube (MNT) and Melamine NanoParticle (MNP) for the adsorption of 5-FU in aqueous media. The MNT was unable to adsorb 5-FU even at high concentration such as 5000 ng/mL. The porous MNP could adsorb around 90% of 5-FU at 5000 ng/mL that outperformed charcoal. Further, I found that porous MNP with hydrophobic linker outperformed the porous MNP with hydrophilic linker. However, the present porous MNP showed no absorption ability with 5-FU at low concentration such as 200 ng/mL or lower. The porous MNP shows a BET surface specific area around 48 m2/g, which may be responsible for the weak 5-FU adsorption at 200 ng/mL. These results pointed that increasing the surface area of MNP shall improve the 5-FU adsorption at low concentration. The lipid for the construction of Melamine NanoTube has been published in scientific journal (Materials Letters, 2019)
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現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
Melamine NanoParticle that can efficiently adsorb 5-FU has been developed, I also found that porous MNP with hydrophobic linker outperformed the porous MNP with hydrophilic linker. The lipid for the construction of Melamine NanoTube has been published in scientific journal (Materials Letters, 2019)
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今後の研究の推進方策 |
The porous MNP should be formulated with higher surface area, either through synthesis process or by using longer alkyl linker, for the adsorption of low concentration 5-FU. The size control of porous MNP and transparent hybrid contact lens seem to be very difficult, therefore turbid hybrid contact lens will be applied for the adsorption experiment at present.
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次年度使用額が生じた理由 |
In the last year, the related results were not presented in domestic symposium. Therefore, domestic travelling expense was left over.
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