| 研究課題/領域番号 |
18K09469
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| 研究機関 | 国立研究開発法人産業技術総合研究所 |
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研究代表者 |
Ding Wuxiao 国立研究開発法人産業技術総合研究所, 材料・化学領域, 主任研究員 (90598757)
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| 研究期間 (年度) |
2018-04-01 – 2022-03-31
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| キーワード | Hybrid hydrogel / Nanotube / Contact lens |
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| 研究実績の概要 |
From 2019/12/01 to 2020/11/30, I was appointed to the International Collaboration Office of my institute. Therefore, the research was almost stopped in the last fiscal year.
I restarted the research from 2020/12/01.
Within the limited time, a hybrid hydrogel was constructed from the PEG polymer and crosslinkable nanotube. The inclusion of nanotube significantly increased the mechanical strength and controlled release property of PEG hydrogel. The nanotube-hybrid hydrogel may have potential application for contact lens. The research result will be published in 2021 fiscal year.
Further, biodegradable supramolecular nanotube tailored for in vivo drug delivery is also under development. We will publish the result of a physiological-responsive nanotube very soon, and will also apply for the Grant-in-Aid for Scientific Research（Ｂ）in 2021 fiscal year.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
The research for the 5-FU adsorption using melamine nanoparticles or melamine-modified nanotubes did not achieve much progress, because of my job movement in the last fiscal year.
However, related researches such as nanotube-hybrid hydrogel and physiological-responsive nanotube progressed smoothly, with their results to be published very soon.
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| 今後の研究の推進方策 |
We will extend the nanotube-hybrid hydrogel into contact lens applications.
A series of physiological-responsive nanotubes, including ROS-responsive and reduction-responsive, will be developed for the drug delivery application.
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| 次年度使用額が生じた理由 |
Dur to my job movement to the International Collaboration Office from 2019/12/01 to 2020/11/30, the research was actually suspended in the first half of 2020 fiscal year.
Further, the COVID-19 pandemic have also prevented the participation of international symposium that has been planned in the last fiscal year.
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