| 研究課題/領域番号 |
18K12024
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| 研究機関 | 国立研究開発法人情報通信研究機構 |
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研究代表者 |
カラン ダニエル 国立研究開発法人情報通信研究機構, 脳情報通信融合研究センター脳機能解析研究室, 主任研究員 (70374113)
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| 研究分担者 |
和田 充史 国立研究開発法人情報通信研究機構, 脳情報通信融合研究センター脳機能解析研究室, 研究員 (10418501)
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| 研究期間 (年度) |
2018-04-01 – 2021-03-31
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| キーワード | tDCS / brain stimulation / EEG / fMRI / neuro modulation / attention / perception |
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| 研究実績の概要 |
The goal of the proposed research is to determine the neural processes underlying the enhancing effects of tDCS. Preliminary data used for this proposal was published in the journal PLoS One. The results of the experiment showed that for a visual search task there are individual differences in learning that correlate with modulation of brain activity induced by transcranial direct current stimulation tDCS. The primary progress on the research conducted during the previous year was in coming up with options for appropriate tasks that are interesting and can elicit good tDCS enhancement effects. We have decided to include EEG as well as fMRI in measuring brain modulation induced by tDCS. Discussion with researchers at UCSD Swartz Center for Computational Neuroscience and researchers at ISAE Supaero, Toulouse France were completed to accomplish these goals. With regards to the analysis of EEG resting state data before and after tDCS we have determined that independent modulator analysis of independent components may be an important means of exploring modulatory changes induced by tDCS that are related to changes in performance. The independent modulator analysis looks at frequency similarities that bind various components together.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
3: やや遅れている
理由
The start of running the tDCS experiments has been slightly delayed because it took about 1 year to purchase the new Starstim high-density tDCS unit. With this new tDCS brain stimulation device we will be able to focally stimulate specific task related regions without having to have unwanted decreases in other brain regions that occurs when using anodal-cathodal traditional stimulation set ups. The addition of this equipment from that of the original proposal is worth this initial delay in that it will greatly improve the focal precision in which we can stimulate which will allow us to better modulate task related performance related to the function of targeted brain regions. One area where we have made some progress is running a preliminary study exploring improvisation in guitar players with EEG. In this study we found that activity in the beta frequency range in the medial frontal cortex and dorsolateral prefrontal cortex was related to playing improvisation music over that of a control condition in which the subjects played scales. We think stimulating the medial frontal cortex with tDCS may induce enhanced improvisation performance. Another study we ran using a dual task involving complex visual motor control and auditory sound detection showed that misses on the auditory task are related to decreased theta band coherence. Stimulation of auditory regions by tDCS may improve auditory processing in these tasks.
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| 今後の研究の推進方策 |
The plan for the research scheme is the following for the remaining two years:
-Add the use of EEG to record brain activity before and after tDCS to determine modulatory effects on performance (Consult with researchers at UCSD SCCN and ISAE Supaero to accomplish this task). The two experiments we are considering now are 1. Improving improvisation performance by stimulating medial frontal cortex by tDCS and 2. Improving auditory perception performance on a dual task paradigm. One task will be the auditory detection task the other will be a visual motor task. By shifting the focus of attention of the task during tDCS stimulation we intend to see differences in the modulation of resting state networks that are specific to behavioral improvements on that task.
-Conduct separate experiments using EEG and fMRI to investigate changes in modulation of resting state activity as it relates to attention selective task processing and later enhancement in performance.
-Analysis of the results using such things as independent modulators for the EEG data and connectivity measures for the fMRI data will be used to determine brain activity related to enhancing effects of tDCS on behavioral performance.
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| 次年度使用額が生じた理由 |
The subject payment fee was not used because it took until February to purchase the new tDCS system so the funds were left over and forwarded to this year.
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