| 研究実績の概要 |
Step 1 of the study has been published in Viruses in 2020 and selected as a cover story of the journal's #11 issue. In Step 2, I have successfully transduced Cas9-gRNA into human mobilized hematopoietic stem cells (HSC) using a lentivector with Cocal virus pseudotyped-envelope. But, Step 3 did not go well as I moved to the US (HIV lab in Harvard), Osaka (Immunology), and now Kobe (Clinical Virology). The labs were not an iPSC lab. iPSC differentiation needed strict protocol and culture environment, and I did not succeed in differentiating the transduced iPSC. I am still hoping to establish a position in an iPSC lab to continue the project.
I prematurely ended the KAKENHI project as I was adopted as a Program-Specific Assistant Professor in Kobe and cannot have any extra research effort.
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