Evaluation of Potential Role of Olive Leaf Extract as A Natural Way to Prevent and Improve Anemia: A randomized Clinical Trial in Japan and Tunisia

2023 年度 実績報告書

• 研究課題/領域番号: 19K20106
• 研究機関: 筑波大学
• 研究代表者: FERDOUSI FARHANA 筑波大学, 生命環境系, 助教 (80820927)
• 研究期間 (年度): 2019-04-01 – 2024-03-31
• キーワード: Olive leaf extract / Anemia / Hemoglobin / Natural compound

研究実績の概要

Our study suggests that a low dose of olive leaf extract (OLE) may hold promise in improving hemoglobin (Hb) levels in both males and females. However, it's important to note that our study was conducted on healthy volunteers with initial Hb values above 12. Additional trials focusing on specific target populations with anemia are necessary to definitively establish OLE's efficacy in improving anemia.

研究成果

• [国際共同研究] icddr,b(バングラデシュ)
  • 国名: バングラデシュ
  • 外国機関名: icddr,b
• [雑誌論文] Hematinic Potential of Olive Leaf Extract: Evidence from an In Vivo Study in Mice and a Pilot Study in Healthy Human Volunteers (2023)
  • 著者名/発表者名: Kondo Shinji、Ferdousi Farhana、Zhao Jinchang、Suidasari Sofya、Yokozawa Miki、Yamauchi Ken、Tominaga Ken-ichi、Isoda Hiroko
  • 雑誌名: Nutrients 巻: 15 ページ: 4095～4095
  • DOI: 10.3390/nu15194095
• [学会発表] A Whole-transcriptomic Study Using a Stem Cell-Based Model for Comparing the Multi-tissue-specific Bioactivities of Rare Olive Compound Oleacein and Oleocanthal (2023)
  • 著者名/発表者名: Farhana Ferdousi, Kazunori Sasaki, Ken-ichi Tominaga, Hiroko Isoda
  • 学会等名: Japanese Association for Animal Cell Technology (JAACT) 2023
• [学会発表] A Comprehensive Bench to Bed Approach to Uncover the Hematological Health Benefits of Olive Leaf Extract (2023)
  • 著者名/発表者名: Farhana Ferdousi
  • 学会等名: Tsukuba Conference 2023
  • 招待講演