| 研究実績の概要 |
This study investigated the associations between bedtime stress and the hemodynamics in the prefrontal cortex (PFC) during the first sleep cycle under free-living conditions. Stress biomarkers including salivary cortisol and secretory immunoglobulin A (sIgA) were measured using the SOMA Dual Analyte LFD test kits on the experiment nights between 22:00-23:00. Perceived stress level was rated on a 1-10 Likert scale right after the collection of the salivary samples. The hemodynamics of the pre-frontal cortex (PFC) was measured using a wearable functional near-infrared spectroscopy (fNIRS) device. Correlation analysis with statistical test was performed to examine the associations between different stress indicators and a set of time-domain and frequency-domain features derived from the hemodynamic responses. Significantly positive linear correlations were observed in the standard deviation, skewness, and kurtosis between the average concentration change of oxyhemoglobin and that of deoxyhemoglobin in the whole region of interest. Stress was found to correlate to the hemodynamics in the mid-DLPFC, the caudal-DLPFC, and the left RLPFC. The relationships between stress and these PFC subregions depends on the stress indicator adopted.
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