Micro-scale, in-vivo structural and functional tomography of rodent habenula using polarization-sensitive optical coherence tomography

2020 年度 研究成果報告書

• 研究課題/領域番号: 19K20674
• 研究種目: 若手研究
• 配分区分: 基金
• 審査区分: 小区分90110:生体医工学関連
• 研究機関: 広島大学
• 研究代表者: カサラゴッド デイーパカマス 広島大学, 医系科学研究科(医), 助教 (40773908)
• 研究期間 (年度): 2019-04-01 – 2021-03-31
• キーワード: Optical Imaging

研究成果の概要

Habenula is a tiny anatomical structure that links the forebrain to the midbrain which regulates pathways associated with a range of behaviors. The proposed research aimed at developing an imaging tool for volumetric assessment of small brain structures like habenula with high resolution.

自由記述の分野

Biomedical Engineering

研究成果の学術的意義や社会的意義

The proposed research developed a cost-effective 3-dimensional (3D) imaging tool that allows for high-throughput and high resolution imaging of brain structures. Serial imaging allows for easy 3D reconstruction for macroscopic quantitative analysis based on the high resolution brain imaging data.