| 研究課題/領域番号 |
20F20346
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| 研究機関 | 国立研究開発法人産業技術総合研究所 |
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研究代表者 |
延 優 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員 (40805644)
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| 研究分担者 |
LENG LING 国立研究開発法人産業技術総合研究所, 生命工学領域, 外国人特別研究員
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| 研究期間 (年度) |
2020-11-13 – 2023-03-31
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| キーワード | Metagenomics / Biotechnology |
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| 研究実績の概要 |
We employed a machine learning-based approach that utilizes two foundational biological features of aromatic compound degradation: activation and organization. The fellow and host successfully identified novel metabolic pathways and organisms involved in utilization and conversion of complex aromatics compounds in wastewater treatment processes. Further evolutionary analyses showed how many contemporarily evolved in plastics industry wastewater streams. The results are expected to bring high impact to the microbiology and engineering communities and will be submitted for publication soon.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
Research proceeded well despite setbacks from COVID-19.
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| 今後の研究の推進方策 |
We successfully identified many genes potentially comprising novel metabolic pathways for aromatic compound degradation. Among these, some were predicted to have evolved very recently and further analyses revealed that these were involved in degradation of xenobiotic pollutants in industrial plastics production wastewater streams, so we will further investigate these novel genes/pathways and their evolutionary history to bring high impact to the microbiology and engineering research community.
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