| 研究課題/領域番号 |
20J10046
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| 研究機関 | 千葉大学 |
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研究代表者 |
TRAN ANH KIET 千葉大学, 融合理工学府, 特別研究員(DC2)
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| 研究期間 (年度) |
2020-04-24 – 2022-03-31
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| キーワード | Malaria / EIS / Single cell / Lung diseases |
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| 研究実績の概要 |
1.Study proposes a novel iRBCs detection method based on 3D multi-shell dielectric model
2.The electric field analysis is performed under control RBC (parasitemia p = 0%) as reference and iRBCs (p = 0.04% to 0.4%). As a result, the electric field analysis results show that the 3D multi-shell dielectric model is applicable to detect iRBCs of parasitemia p with maximum error of 0.056.
3.3D multi-shell dielectric model describes the dielectric properties of iRBCs as a function of parasitemia p to estimate p from the dielectric properties obtained from electrical impedance spectra.
4.Also I proposed the development of a biosensor system for high accuracy single cell identification as well as inspire the development of a diagnostic device for early fetal lung diseases based on the neEIS system.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
1: 当初の計画以上に進展している
理由
The research progress is as expected. The study focuses on the dielectric properties of iRBCs as a function of parasitemia p to estimate p from the dielectric properties obtained from electrical impedance spectra. The research goal plans are achieved.
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| 今後の研究の推進方策 |
The clinical study will concentrate on intense analytical validation with a lab on chip CD type EIS hardware which was made in year 2020 in Takei lab by using malaria parasite-infected primates conducted in collaboration with Chiba University Hospital further limited field testing at Chiba University Hospital in Japan.
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| 備考 |
http://www.em.eng.chiba-u.jp/~takei/papers.html
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