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2021 年度 実施状況報告書

Reconstruction of dose distributions using PET images in heavy ion therapy

研究課題

研究課題/領域番号 20K08066
研究機関国立研究開発法人量子科学技術研究開発機構

研究代表者

Mohammadi Akram  国立研究開発法人量子科学技術研究開発機構, 先進核医学基盤研究部, 主任研究員 (10554735)

研究期間 (年度) 2020-04-01 – 2023-03-31
キーワードdose reconstruction / PET image / ion therapy
研究実績の概要

A spread-out Bragg peak (SOBP) of 3 cm was produced for a C-12 beam (350 MeV/u) using a designed range modulator in the carbon therapy facility of the Heavy Ion Medical Accelerator in Chiba (HIMAC). Dose and PET data for C-12 beams with several energies for a PMMA phantom were prepared using Monte Carlo simulation (Phits code). The algorithm for converting PET data to dose distribution and its optimization are still under development.

現在までの達成度 (区分)
現在までの達成度 (区分)

2: おおむね順調に進展している

理由

The progress of the research was almost according to the original plan and there was no problem by now.

今後の研究の推進方策

For the next fiscal year, a head and neck phantom will be simulated and experimentally irradiated with both C-11 and C-12 beams (pristine Bragg peak and SOBP) in the HIMAC. The optimization of the algorithm for dose estimation using PET data for both C-11 and C-12 beams will be performed for the head and neck phantom.

次年度使用額が生じた理由

The required items and devices were available therefore any item was not purchased.

  • 研究成果

    (1件)

すべて 2021

すべて 雑誌論文 (1件) (うち国際共著 1件、 査読あり 1件)

  • [雑誌論文] Development of dual-ended depth-of-interaction detectors using laser-induced crystals for small animal PET systems2021

    • 著者名/発表者名
      Akram Mohammadi, Naoko Inadama, Fumihiko Nishikido, Taiga Yamaya
    • 雑誌名

      Physics in Medicine & Biology

      巻: 66 ページ: 175029-1-13

    • DOI

      10.1088/1361-6560/ac18fc

    • 査読あり / 国際共著

URL: 

公開日: 2022-12-28  

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