| 研究課題/領域番号 |
20K11597
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| 研究機関 | 北海道大学 |
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研究代表者 |
Amengual Olga 北海道大学, 医学研究院, 講師 (10636939)
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| 研究分担者 |
渥美 達也 北海道大学, 医学研究院, 教授 (20301905)
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| 研究期間 (年度) |
2020-04-01 – 2023-03-31
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| キーワード | Rheumatoid arthritis / Diet / Fish consumption / n-3 PUFAs |
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| 研究実績の概要 |
During the first year, we researched food frequency questionnaires and, after consultation with nutritionists, the brief type self-administered diet history questionnaire (BDHQ) was selected and purchased. Japanese BDHQ was officially translated into Spanish. Another dietary questionnaire focusing on fish consumption was prepared and adapted to Spanish and Japanese population. We drafted the retrospective study protocol, patient's informed consent and data collection sheet in Japanese and Spanish. The documents were submitted to the Institutional Review Board of the two participating hospitals in Japan and Spain. By reviewing the medical records, patients with rheumatoid arthritis who were being treated with targeted therapies were identified.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
We are currently printing the BDHQ officially translated into Spanish and the dietary questionnaire focusing on specific fish consumption in Spanish and Japanese. We were unable to print the questionnaires before obtaining approval from the Institutional Review Board of the two hospitals participating in the study.
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| 今後の研究の推進方策 |
In the second year we will perform dietary assessments in patients with rheumatoid arthritis (RA) who have received targeted therapies. Data from the dietary questionnaires, as well as from medical reports will be collected.
We are also planning to conduct the prospective phase of the study in RA patients starting a new targeted therapy, after obtaining Institutional Review Board approval of the application for the prospective non-intervention study.
In the third year, we will continue to include patients in both the retrospective and prospective phases, if it has not been possible to reach the estimated number of patients during the second year of this study.
All data from the two cohorts will be tabulated and analysed. The results obtained in this research will be presented at national and international conferences and will be prepared for publication in academic journals.
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| 次年度使用額が生じた理由 |
コロナ禍により、スペイン国との共同研究研究者の打合せおよび、実施に遅れが生じているため、旅費およびアンケートの印刷の執行ができなかった。オンラインでの打ち合わせを確立したため、次年度はすすめてゆくことができる見込み。旅費計上分は、コロナの状況を見ながら、通信費、郵送費など研究実施のため転換して計画してゆく。
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