| 研究実績の概要 |
We demonstrated a novel on-chip biosensor, which is composed of a metal-free (i.e., without localized surface plasmon resonance), topologically tailored porous carbon nanowires in an array to overcome the unreliability of surface-enhanced Raman spectroscopy (SERS) for biomedical use. Specifically, the biosensor offers not only high signal enhancement (~1,000,000) due to its strong broadband charge-transfer resonance, but also extraordinarily high reproducibility due to the absence of hot spots. In addition, the biosensor exhibits high durability due to no oxidization and high compatibility to biomolecules due to its fluorescence quenching capability. The biosensor is expected to lead to high reliability of SERS for practical use.
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| 今後の研究の推進方策 |
Based on the design, fabrication, and characterization experience we have accumulated for developing the on-chip biosensor based on surface-enhanced Raman spectroscopy this fiscal year, we will go further to realize the on-chip chiral biosensor based on Raman optical activity by optimizing the design and the characterization system of the biosensor in the following years.
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