| 研究実績の概要 |
As described in the previous research report, the research direction had deviated from the original plan, as we were not successful in using the DATB catalyst in tandem with transition metals to access novel reaction pathways. We then aimed to synthesize, characterize and test the catalytic activity of N(BOH)2-containing molecules. This moiety is structually similar to DATB, but no synthetic pathways to produce it were present in the literture. Fortunately, we were successful in our endevour, producing a shelf-stable compound that was even more catalytically active than the DATB catalyst. The work was published in Org. Lett. (2023, 25, 4, 694-697). This novel catalytically-active moiety likely provides a novel mode of action for amide activation, which warrants further investigation.
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