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2022 年度 実績報告書

The potential beneficial effects of inactivated Bifidobacterium Longum on the alleviation of muscle atrophy and physical fatigue in aged hospitalized and athletes using in vitro and in vivo models.

研究課題

研究課題/領域番号 20K15466
研究機関筑波大学

研究代表者

BEN・OTHMAN MAHMOUD  筑波大学, 健幸イノベーション開発研究センター, 研究員 (40868337)

研究期間 (年度) 2020-04-01 – 2023-03-31
キーワードMuscle atrophy / Treadmill / Power strength
研究実績の概要

In order to evaluate the effect of Bifidobacterium longum extract on anti-fatigue and muscles atrophy in mice, we perform some exercises on mice. We created a muscles atrophy by cast immobilization of mouse's hindlimb for 10 days.
The results showed a significant increase of running distance of BL-treated mice compared with non-treated mice. Moreover, the power strength of muscles was significantly increased in dose dependent manner in treated groups compared with non-treated group. Finally, BL at 50mg/kg significantly increased the muscles weight compared with non-treated mice.

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公開日: 2023-12-25  

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