冠動脈インターベンションの国際比較と質的向上を目指したデータベース構築

2010 年度 研究成果報告書

• 研究課題/領域番号: 21790751
• 研究種目: 若手研究(B)
• 配分区分: 補助金
• 研究分野: 循環器内科学
• 研究機関: 慶應義塾大学
• 研究代表者: 香坂 俊 慶應義塾大学, 医学部, 助教 (30528659)
• 研究期間 (年度): 2009 – 2010
• キーワード: 循環器 / 高血圧

研究概要

レジストリ登録されたデータを用いて(15施設、4000例)、PCI に伴ってみられた出血合併症の発症率の計算を行い、関連する臨床的因子の寄与度の定量化を行った。さらには、PCI施行後の適切な処方の用いられ方、そして休日と週末のPCI入院による実際の成績の違い等に関しての解析を行い、その結果を平成23年3月に行われた日本循環器学会にて発表、現在論文として学術誌に順次投稿している。また、四半期に一度程度継続的なフィードバックをかけて各施設の医療の質の向上に努めている。

研究成果

• [雑誌論文] Arterial wave reflection and subclinical left ventricular systolic dysfunction. (2011)
  • 著者名/発表者名: Russo C, Jin Z, Takei Y, Hasegawa T, Koshaka S, Palmieri V, Elkind MSHomma S, Sacco RL, Di Tullio MR.
  • 雑誌名: J Hypertens. 29(3) ページ: 574-582
  • 査読あり
• [雑誌論文] Elevated inflammatory markers in heart failure patients with lower BMI. (2011)
  • 著者名/発表者名: Banno A, Kohsaka S, Yoshikawa T.
  • 雑誌名: J Card Fail. 17(3) No abstract available. ページ: 264
  • 査読あり
• [雑誌論文] Elevated B-type natriuretic peptide level as a marker of subsequent thromboembolic events in patients with atrial fibrillation. (2010)
  • 著者名/発表者名: Sadanaga T, Kohsaka S, Mitamura H, Ogawa S.
  • 雑誌名: Heart Vessels. [Epub ahead of print]
  • 査読あり
• [雑誌論文] D-dimer levels in combination with clinical risk factors can effectively predict subsequent thromboembolic events in patients with atrial fibrillation during oral anticoagulant therapy. (2010)
  • 著者名/発表者名: Sadanaga T, Kohsaka S, Ogawa S.
  • 雑誌名: Cardiology. 117(1) ページ: 31-36
  • 査読あり
• [雑誌論文] Relationship between Serum Lipid Values and Atherosclerotic Burden in the Proximal Thoracic Aorta. (2010)
  • 著者名/発表者名: Kohsaka S, Sacco RL, Jin Z, Liu R, Rundek T, Boden-Albala B, Homma S, Di Tullio MR.
  • 雑誌名: Int J Stroke. 5(4) ページ: 257-263
  • 査読あり
• [雑誌論文] Difference in Patient Profiles and Outcomes in Japanese Versus American Patients Undergoing Coronary Revascularization : A Collaborative Study by CREDO-Kyoto and the Texas Heart Institute Research Database. (2010)
  • 著者名/発表者名: Kohsaka S, Kimura T, Goto M, Lee VV, Elayda MA, Furukawa Y, Fukushima M, Komeda M, Sakata R, Willerson, JT, Wilson, JM, Kita T.
  • 雑誌名: Am J Cordial. 105(12) ページ: 1698-1704
  • 査読あり
• [雑誌論文] Ogawa Elevated troponin T on discharge predicts poor outcome of decompensated heart failure. (2010)
  • 著者名/発表者名: Koide K, Yoshikawa T, Nagatomo Y, Kohsaka S, Anzai T, Meguro T
  • 雑誌名: Heart Vessels. 25(3) ページ: 217-222
  • 査読あり
• [雑誌論文] J-RHYTHM Investigators. Impact of drug alteration to maintain rhythm control in paroxysmal atrial fibrillation : Subanalysis from J-RHYTHM study. (2010)
  • 著者名/発表者名: Endo A, Kohsaka S, Suzuki S, Atarashi H, Kamakura S, Sakurai M, Nakaya H, Fukatani M, Mitamura H, Yamazaki T, Yamashita T, Ogawa S.
  • 雑誌名: Circ J. 74(5) Epub 2010 Apr 3. ページ: 870-875
  • 査読あり
• [雑誌論文] J-RHYTHM Investigators. Efficacy and Safety of Antiarrhythmics Used in Patients with Paroxysmal Atrial Fibrillation : sub-analysis of J-RHYTHM study. (2010)
  • 著者名/発表者名: Aizawa Y, Kohsaka S, Suzuki S, Atarashi H, Kamakura S, Sakurai M, Nakaya M, Fukatani M, Mitamura H, Yamazaki T, Yamashita T, Ogawa S.
  • 雑誌名: Circ J. 74(1) Epub2009 Dec 2. ページ: 71-76
  • 査読あり
• [学会発表] Who will not Receive Optimized Medical Therapy after Percutaneous Coronary Intervention? Analysis from Japanese Prospective Multicenter Registry. (2011)
  • 著者名/発表者名: Endo A, Kohsaka S, Miyata H, Kawamura A, Noma S, Suzuki M, Koyoma T, Ishikawa S, Momiyama Y, Nakagawa S, Sueyoshi K, Takagi S, Takahashi T, Takamoto S, Ogawa S, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-20
• [学会発表] Percutaneous Coronary Intervention for Acute Coronary Syndrome; Comparison between Weekend Versus Weekday Presentation. (2011)
  • 著者名/発表者名: Mogi S, Kohsaka S, Fukuda k, Miyata H, Noma S, Suzuki M, Koyoma T, Ishikawa S, Sueyoshi K, Takagi S, Takahashi T, Takamoto S, Ogawa S.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-20
• [学会発表] Bleeding Complication in Patients Undergoing PCI ; a Report from Multicenter Prospective Registry. (2011)
  • 著者名/発表者名: Takahashi M, Kohsaka S, Miyata H, Kawamura A, Noma S, Suzuki M, Koyoma T, Ishikawa S, Hiyama Y, Nakagawa S, Sueyoshi K, Takagi S, Takahashi T, Takamoto S, Numasawa Y, Endo A, Mogi S, Ogawa S, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-19
• [学会発表] The Relevance of Killip Classification in Patients with Acute Heart Failure Syndrome. (2011)
  • 著者名/発表者名: Miyamoto T, Sakai T, Takagi A, Harada k, Kohsaka S, Iida K, Satoh N, Nagao K, Takayama M.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-19
• [学会発表] Perioperative Cardiac Risk of Noncardiac Surgery after Drug Eluting Stent Implantation. (2011)
  • 著者名/発表者名: Ohno Y, Kawamura A, Mogi S, Takahashi M, Endo A, Numasawa Y, Arai T, Yuasa S, Kohsaka S, Furuta A, Maekawa Y, Kimura K, Sano M, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-19
• [学会発表] Fukuda KClinical Predictors for Sustained Ventricular Tachyarrhythmia and Advanced AV Block in Patients with Cardiac Sarcoidosis. (2011)
  • 著者名/発表者名: Nishiyama N, Satoh T, Nagai T, Kimura T, Fukumoto K, Aizawa Y, Kohsaka S, Karube Y, Miyoshi S, Takatsuki S, Ogawa S
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-19
• [学会発表] Effect of Preprocedural Antiplatelets on Peak Cardiac Enzyme Values in PCI Patients with Acute Coronary Syndrome. (2011)
  • 著者名/発表者名: Ikegami Y, Kohsaka S, Miyata H, Kawamura A, Noma S, Suzuki M, Koyama T, Ishikawa S, Momiyama Y, Nakagawa S, Sueyoshi K, Takagi S, Takahashi T, Takamoto S, Ogawa S, Fukuda k.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-19
• [学会発表] Long-term Predictors ofICD Shocks in patients with Brugada Syndrome. (2011)
  • 著者名/発表者名: Aizawa Y, Sato T, Kohsaka S, Maeda A, Kimura T, Nishiyama N, Fukumoto K, Fukuda Y, Miyoshi S, Takatsuki S, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-18
• [学会発表] Significance of Electrocardiographic Right Ventricular Hypertrophy in Patients with Pulmonary Hypertension with or without Right Ventricular Dysfunction. (2011)
  • 著者名/発表者名: Nagai T, Kohsaka S, Murata M, Anzai T, Sato T, Fukuda k.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-18
• [学会発表] Outcomes of Percutaneous Coronary Intervention in Octogenarians with Acute Coronary Syndrome ; Crude Comparison of Drug Eluting vs. Bare Metal Stents. (2011)
  • 著者名/発表者名: Maekawa Y, Kohsaka S, Miyata H, Ishikawa S, Koyoma T, Sueyoshi K, Suzuki M, Takagi S, Takahashi T, Nakagawa S, Noma S, Momiyama Y, Takamoto S, Kawamura A, Ogawa S, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-18
• [学会発表] Elevaed B-type Natriuretic Peptide Level as a Maker of Subsequent Thromboembolic Events in Patienys, with Atrial Fibrillation. (2011)
  • 著者名/発表者名: Sadanaga T, Kohsaka S, Mitamura H.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-18
• [学会発表] Left Atrial Reservoir Function in Patients with Atrial Fibrillation: Relation with Left Atrial Appendage Flow Velocity. (2011)
  • 著者名/発表者名: Tsuruta H, Iwanaga S, Murata M, Yasuda R, Kohsaka S, Kimura T, Nishiyama N, Aizawa Y, Miyashi S, Takatsuki S, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-18
• [学会発表] Safety of Transradial Approach for Percutaneous Coronary Intervention in the Japanese Multicenter Registry. (2011)
  • 著者名/発表者名: Numasawa Y, Kohsaka S, Miyata H, Kawamura A, Noma S, Suzuki M, Koyama T, Ishikawa S, Momiyama Y, Nakagawa S, Sueyoshi K, Takagi S, Takahashi T, Takamoto S, Ogawa S, Fukuda K.
  • 学会等名: The 75th Annual Scientific Meeting of the Japanese Circulation Society.
  • 発表場所: Yokohama, Japan.
  • 年月日: 2011-03-18
• [学会発表] Impact of serum biomarkers by the presence or absence of kidney disease in predicting long-term outcome among advanced systolic heart failure patients. (2010)
  • 著者名/発表者名: Kohsaka S.
  • 学会等名: XX World Congress ISHR
  • 発表場所: Kyoto Japan
  • 年月日: 2010-05-14