| 研究課題/領域番号 |
21H01383
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| 研究機関 | 東京大学 |
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研究代表者 |
J・J Delaunay 東京大学, 大学院工学系研究科(工学部), 准教授 (80376516)
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| 研究分担者 |
何 亜倫 東京大学, 大学院工学系研究科(工学部), 助教 (20815386)
松井 裕章 東京大学, 大学院工学系研究科(工学部), 准教授 (80397752)
古川 克子 東京大学, 大学院工学系研究科(工学部), 准教授 (90343144)
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| 研究期間 (年度) |
2021-04-01 – 2024-03-31
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| キーワード | surface wave / light confinement / optical switching / optcial sensing |
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| 研究実績の概要 |
In this fiscal year, we have designed, fabricated, and tested an interferometric sensing device based on our Bloch surface wave platform. In the proposed device, a Bloch-surface wave is excited at the interface between a truncated one-dimensional photonic crystal and air, and the wave is made to interfere between two grating structures. The two grating structures are also used to couple the light in and out of the device. Interference patterns are recorded by sweeping the wavelength of the incident light and recording the intensity of the outcoupled light using our homemade microscope setup. After surface modification using a protein-ligand scheme, a shift in the interference pattern was determined. The limit of detection of the proposed unlabeled detection scheme was found to be 10 fg/mL.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
We have proposed and demonstrated a new biochemical sensing scheme based on the Bloch surface wave platform and thus added one functionality (sensing) to our platform as explained in the original proposal. The original design has been modified and improved using simulation, and the optical setup has been adapted to measure the response of the proposed device. The predicted sensing performance of the proposed design is well reproduced using numerical simulations so we are confident that we have now reached the proof of concept stage.
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| 今後の研究の推進方策 |
Additional modifications of our homemade optical setup will be introduced to improve the quality of the collected signal in terms of stability and signal-to-noise ratio. The modified setup will be used to double-check the results obtained in the second year. Validation of the experimental results will be conducted by reproducing the experiments and estimating uncertainty in the detection of the biomaterials. A physical model will be proposed to explain our findings and this model will be used as a guide to optimize the proposed device. Our results will be submitted to a journal.
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