| 研究課題/領域番号 |
21K07554
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| 研究機関 | 沖縄科学技術大学院大学 |
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研究代表者 |
TAOUFIQ Zacharie 沖縄科学技術大学院大学, 細胞分子シナプス機能ユニット, スタッフサイエンティスト (10549348)
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| 研究期間 (年度) |
2021-04-01 – 2024-03-31
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| キーワード | Synapse / Deep proteomics / Schizophrenia / Mental disorders / iPS-derived neurons |
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| 研究実績の概要 |
In collaboration with the Budapest Research Center for Natural Sciences, I have received analyzed 3 new iPSC samples coming from Caucasian family having a living schizophrenia individual. The synapse proteomics analysis revealed significant impaired expression of some specific lipid metabolic enzymes compared healthy.
I have started a collaboration with RIKEN AIP for building AI/Machine learning tools to interpret and analyze synapse proteomics data from our psychiatric patient cohort.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
I have succeed the analysis of 3 new iPSC samples.
The collaboration with RIKEN AIP for building AI/Machine learning tools is on going.
I plan a second travel to visit collaborators next month.
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| 今後の研究の推進方策 |
I am planning to receive new schizophrenia samples and start comparing them with bipolar disease.
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| 次年度使用額が生じた理由 |
I could not get all samples on time due to delay in Human sample research committee approval processes.
This remaining budget will be used to cover the cell lines fee in 2023.
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