| 研究課題/領域番号 |
21K15583
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| 研究機関 | 大学共同利用機関法人高エネルギー加速器研究機構 |
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研究代表者 |
PANT Amba・Datt 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 研究員 (60760121)
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| 研究期間 (年度) |
2021-04-01 – 2024-03-31
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| キーワード | Hypoxia / muon and muonium / tumor / cancer |
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| 研究実績の概要 |
In order to apply the muon in cancer research, main goal of this research is to detect the molecular oxygen in biosamples using muon method.
Since the water and molecular oxygen are existed in the biosamples, I have planned to perform systematic study starting from water, oxygen dependent in water, buffer and biosamples. So far, I have studied the muon and muonium behavior in water. The stopping site of muon in ice has been found for the first time and the data were explained satisfactorily using new model. As a next step, oxygen dependent study in water will be performed. Then, the detection of oxygen in biosamples (hemoglobin, blood plasma) and inhomogeneous system of hemoglobin and blood plasma will be performed within the project period.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
Since the water can not be separated from the biosample, I have studied the muon behavior in water. I have found stopping sites of muon in water/ice for the first time and modeled the data satisfactory. This data is going to publish in high indexed journal (a paper in under review in Physical Review Letter). This achievement will provide the new insight into existing muon science field.
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| 今後の研究の推進方策 |
In addition of water, molecular oxygen are also exited in biosamples. So the experiment proposals for oxygen dependent study are proposed in MLF, J-PARC and RIKEN-RAL. A proposal at MLF for 2022A round of beamtime has already got approved. Oxygen dependent muon behavior in water, buffer, hemoglobin, blood plasma and inhomogenous system will be performed.
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| 次年度使用額が生じた理由 |
Muon experiment at MLF, J-PARC and RIKEN-RAL.
To purchase the samples, prepare setup and transportation.
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