研究実績の概要 |
This project demonstrated the viability of using artificial intelligence to design therapeutic proteins for a rare disease. We used the latest methods to generate almost 200 candidate molecules, that are now undergoing in vitro testing by a collaborator at the Jichi Medical University Hospital. This number consists a dramatic reduction in the number of candidates that is traditionally tested in pre-clinical studies. Importantly, we generated our therapeutic proteins using a technique called cell-free expression, which does not involve the use of any bacteria or mammalian cell lines; this further reduced the costs and labor involved in the process. Overall, we are satisfied with the progress of this project, the conscious use of resources and the training of younger researchers.
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