| 研究課題/領域番号 |
22K06490
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| 研究機関 | 沖縄科学技術大学院大学 |
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研究代表者 |
Lindeman Sander 沖縄科学技術大学院大学, 知覚と行動の神経科学ユニット, ポストドクトラルスカラー (50866192)
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| 研究分担者 |
フクナガ イズミ 沖縄科学技術大学院大学, 知覚と行動の神経科学ユニット, 准教授 (90801259)
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| 研究期間 (年度) |
2022-04-01 – 2025-03-31
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| キーワード | Neurosicence / State-dependent / Inhibition / Sensory Processing |
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| 研究実績の概要 |
In FY 2022 we have successfully ran experiments to identify subcellular specificity of sate-dependent inhibition. We have recorded neural activity from different compartments of two types of output neurons in the olfactory bulb. With these data we were able to identify where in these cells (in which compartments) inhibition occurred in a behavioural relevant context. We thus have successfully reach our milestone for this fiscal year. In addition, we started to run experiments to identify the source of this inhibition. The preliminary results were shared at a major international neuroscience conference in November and have been positively received by our peers.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
Research progress is according to initial plan. No major set-backs encountered.
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| 今後の研究の推進方策 |
We set out to identify the source of the inhibition that we observed in the output neurons in the olfactory bulb. For this, we recently have started to record activity from the inhibitory granule cells, located deep in the olfactory bulb. These neurons mediate feedback information from a specific higher order brain region into the olfactory bulb. These data will shed light on which higher order brain regions are potentially involved in modulating state-dependent sensory processing in the olfactory bulb.
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