| 研究課題/領域番号 |
22K12384
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| 研究機関 | 国立研究開発法人量子科学技術研究開発機構 |
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研究代表者 |
楊 国勝 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所 計測・線量評価部, 主任研究員 (10801227)
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| 研究分担者 |
金 ウンジュ 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所 計測・線量評価部, 主幹研究員 (10370876)
鄭 建 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所 計測・線量評価部, 上席研究員 (30370878)
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| 研究期間 (年度) |
2022-04-01 – 2025-03-31
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| キーワード | Atctinides / Bioassay / Radiation emergency / PROCORAD intercomparison / ICP-MS/MS / Alpha spectrometry |
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| 研究実績の概要 |
The developed urinary bioassay methods in last year were applied to measured U, Pu, and Am isotopes by ICP-MS/MS in the urinary samples collected during the Oarai Pu/Am exposure accident. The data of ICP-MS/MS were comparable with that of alpha spectrometry. In addition, the developed urinary and fecal bioassay methods were also applied to participate in the annual intercomparison organized by PROCORAD, France. Based on the performance criteria including Z-score, bias, and En value, our lab qualified as TOP LABO for these comparisons: Actinides in urine with DTPA (2023), Actinides in urine (2023), and Uranium in fecal ashes (2023). These indicated the developed urinary and fecal bioassay methods are able to measure actinides rapidly in urinary and fecal samples.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
3: やや遅れている
理由
This year, we focused on the application of the developed urinary and fecal bioassay methods to measure actinides in contaminated urinary samples and participate in interlaboratory comparison for method validation. The development of bioassay method in blood to measure actinides was somewhat delayed.
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| 今後の研究の推進方策 |
The development of fecal bioassay method to measure actinides by ICP-MS/MS are expected to be published as papers. The development of bioassay method for the measurement of actinides in blood sample will be performed in this year. The remaining urinary samples collected during the Oarai Pu/Am exposure accident will be measured by the developed methods with ICP-MS/MS, to compare with that of alpha spectrometry. In addition, the developed methods could also provide additional information, such as the 240Pu/239Pu atom ratio, uranium isotopes.
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| 次年度使用額が生じた理由 |
For the method development to measure actinides in blood samples, blood samples, required reagents and materials (e.g. acid to decompose organic matters in blood, resin cartridge for purification of actinides in blood) for experiment are to be purchased.
In order communicate with other researchers and obtain the latest information, I also want to use the budget to participate in domestic and international conferences.
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