フェムト秒波長可変レーザーイオン化質量分析計の開発とその科学計測への応用

2013 年度 研究成果報告書

• 研究課題/領域番号: 23245017
• 研究種目: 基盤研究(A)
• 配分区分: 補助金
• 応募区分: 一般
• 研究分野: 分析化学
• 研究機関: 九州大学
• 研究代表者: 今坂 藤太郎 九州大学, 工学(系)研究科(研究院), その他 (30127980)
• 研究期間 (年度): 2011-04-01 – 2014-03-31
• キーワード: 超高感度レーザーイオン化質量分析 / 紫外イオン化レーザー光源 / 網羅分析 / 爆発物 / PM2.5 / ダイオキシン / PCB / 農薬

研究概要

２色のフェムト秒レーザー光を水素ガスと相互作用させ、波長185 nmから600 nmに亘る多色超短パルス光源を得た。質量分析計において新規試料導入法を研究し、従来法より2倍高い検出感度を得た。波長200 nmの深紫外超短パルス光を用いて非共役二重結合を有する化合物の検出感度を2倍から100倍向上した。TATPの分子イオン検出、血液中での生成機構を研究した。PCDF, PCDD, PCB計32種の化合物、近年社会問題となっているPM2.5に含まれるPAH、NPAHの網羅的分析を行った。多色紫外超短パルス光源を爆発物の分析へ応用し、実用性を示した。

研究成果

• [雑誌論文] Autocorrelator for Measuring an Ultrashort Optical Pulse Width in the Ultraviolet Region Based on Two-Photon Ionization of an Organic Compound (2014)
  • 著者名/発表者名: T. Okuno, T. Imasaka, Y. Kida, T. Imasaka
  • 雑誌名: Opt. Commun 巻: Vol.310 ページ: 48-52
  • DOI: 10.1016/j.optcom.2013.07.055
  • 査読あり
• [雑誌論文] Simple Pretreatment Procedure Combined with Gas Chromatography/Multiphoton Ionization/Mass Spectrometry for the Analysis of Dioxins in Soil Samples Obtained after the Tōhoku Earthquake (2013)
  • 著者名/発表者名: Y.-C. Chang, T. Imasaka
  • 雑誌名: Anal. Chem 巻: Vol.85 ページ: 349-354
  • DOI: 10.1021/ac3028917
• [雑誌論文] Ionization of Pesticides Using a Far-Ultraviolet Femtosecond Laser in Gas Chromatography/Time-of-Flight Mass Spectrometry (2013)
  • 著者名/発表者名: Y. Hashiguchi, S. Zaitsu, T. Imasaka
  • 雑誌名: Anal. Bioanal. Chem 巻: Vol.405 ページ: 7053-7059
  • DOI: 10.1007/s00216-013-6976-0
  • 査読あり
• [雑誌論文] The Search for a Molecule to Measure an Autocorrelation Trace of the Second/Third Harmonic Emission of a Ti : sapphire Laser Based on Two-Photon Resonant Excitation and Subsequent One Photon Ionization (2013)
  • 著者名/発表者名: T. Imasaka, T. Okuno, T. Imasaka
  • 雑誌名: Appl. Phys. B 巻: Vol.113 ページ: 543-549
  • DOI: 10.1007/s00340-013-5505-3
  • 査読あり
• [雑誌論文] Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry Using a Femtosecond Laser (2013)
  • 著者名/発表者名: T. Imasaka
  • 雑誌名: Anal. Bioanal. Chem 巻: Vol.405 ページ: 6907-6912
  • DOI: 10.1007/s00216-013-6960-8
  • 査読あり
• [雑誌論文] Determination of Persistent Organic Pollutants by Gas Chromatography/Laser Multiphoton Ionization/Time-of-Flight Mass Spectrometry (2012)
  • 著者名/発表者名: O. Shitamichi, T. Matsui, Y. Hui, W. Chen, T. Imasaka
  • 雑誌名: Frontiers Environ. Sci. Eng. China 巻: Vol.16 ページ: 26-31
  • DOI: 10.1007/s11783-011-0374-7
  • 査読あり
• [雑誌論文] An Ultrashort-Duration, High-Repetition-Rate Pulse Source for Laser Ionization/Mass Spectrometry (2012)
  • 著者名/発表者名: T. Uchimura, N. Nakamura, T. Imasaka
  • 雑誌名: Rev. Sci. Instrum 巻: Vol.83 ページ: 014101/1-4
  • DOI: 10.1063/1.3675890
  • 査読あり
• [雑誌論文] Analysis of Persistent Organic Pollutants at Sub-Femtogram Levels Using a High-Power Picosecond Laser in Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry (2012)
  • 著者名/発表者名: T. Matsui, K. Fukuzawa, M. Fujimoto, T. Imasaka
  • 雑誌名: Anal. Sci 巻: Vol.28 ページ: 445-450
  • DOI: 10.2116/analsci.28.445
  • 査読あり
• [雑誌論文] Unexpected Signals in Gas Chromatograph/Multiphoton Ionization/Time-of-Flight Mass Spectrometer Designed for the Detection of Negatively Charged Species (2012)
  • 著者名/発表者名: H. Okudaira, T. Uchimura, T. Imasaka
  • 雑誌名: Anal. Sci 巻: Vol.28 ページ: 683-687
  • DOI: 10.2116/analsci.28.683
  • 査読あり
• [雑誌論文] Searching for a Molecule with a Wide Frequency Domain for Non-Resonant Two-Photon Ionization to Measure the Ultrashort Optical Pulse Width (2012)
  • 著者名/発表者名: T. Imasaka, T. Imasaka
  • 雑誌名: Opt. Commun 巻: Vol.285 ページ: 3514-3518
  • DOI: 10.1016/j.optcom.2012.04.015
  • 査読あり
• [雑誌論文] High-Order Raman Sidebands Generated from the Near-Infrared to Ultraviolet Region by Four-Wave Raman Mixing of Hydrogen Using an Ultrashort Two-Color Pump Beam (2012)
  • 著者名/発表者名: O. Shitamichi, T. Imasaka
  • 雑誌名: Opt. Express 巻: Vol.20 ページ: 27959-27965
  • DOI: 10.1364/OE.20.027959
  • 査読あり
• [雑誌論文] Analysis of Dioxins by Gas Chromatography/Resonance-Enhanced Multiphoton Ionization/Mass Spectrometry Using Nanosecond and Picosecond Lasers (2011)
  • 著者名/発表者名: A. Li, T. Uchimura, Y. Watanabe-Ezoe, T. Imasaka
  • 雑誌名: Anal. Chem 巻: Vol.83 ページ: 60-66
  • DOI: 10.1021/ac101849w
  • 査読あり
• [雑誌論文] Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry of Polychlorinated Biphenyls (2011)
  • 著者名/発表者名: T. Matsui, T. Uchimura, T. Imasaka
  • 雑誌名: Anal. Chim. Acta 巻: Vol.694 ページ: 108-114
  • DOI: 10.2116/analsci.22.1483
  • 査読あり
• [雑誌論文] Polychlorinated Aromatic Hydrocarbons in a Soil Sample Measured Using Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry (2011)
  • 著者名/発表者名: N. Nakamura, T. Uchimura, Y. Watanabe-Ezoe, T. Imasaka
  • 雑誌名: Anal. Sci 巻: Vol.27 ページ: 617-622
  • DOI: 10.2116/analsci.27.617
  • 査読あり
• [雑誌論文] Analysis of Pesticides by Gas Chromatography/Multiphoton Ionization/Mass Spectrometry Using a Femtosecond Laser (2011)
  • 著者名/発表者名: A. Li, T. Imasaka, T. Uchimura, T. Imasaka
  • 雑誌名: Anal. Chim. Acta 巻: Vol.701 ページ: 52-59
  • 査読あり
• [雑誌論文] Multiphoton Ionization/Mass Spectrometry of Polybrominated Diphenyl Ethers (2011)
  • 著者名/発表者名: O. Shitamichi, T. Imasaka, T. Uchimura, and T. Imasaka
  • 雑誌名: Anal. Method 巻: Vol.3 ページ: 2322-2327
  • 査読あり
• [学会発表] Analysis of Persistent Organic Pollutants at Sub-Femtogram Levels by Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry Using a High-Power Picosecond Laser (2013)
  • 著者名/発表者名: Taiki Matsui, Kodai Fukazawa, Masatoshi Fujimoto, Totaro Imasaka
  • 学会等名: Asianalysis XI
  • 発表場所: Nanjing China
  • 年月日: 2013-08-24
• [学会発表] Analysis of Persistent Organic Pollutants at Sub-Femtogram Levels by Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry Using a High-Power Picosecond Laser (2013)
  • 著者名/発表者名: Taiki Matsui, Kodai Fukazawa, Masatoshi Fujimoto, Totaro Imasaka
  • 学会等名: Asianalysis XII
  • 発表場所: Maidashi campus of Kyushu University
  • 年月日: 2013-08-24
• [学会発表] Improvement of Sensitivity in Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry by Optimizing the Separation Column (2013)
  • 著者名/発表者名: Yuanyuan Tang, Totaro Imasaka
  • 学会等名: ASIANALYSIS XII
  • 発表場所: Maidashi campus of Kyushu University
  • 年月日: 2013-08-24
• [学会発表] Mass Spectrometer for Measuring an Autocorrelation Trace of an Ultrashort Optical Pulse in the Ultraviolet Region Based on Two-Photon Ionization of an Organic Compound (2013)
  • 著者名/発表者名: Tomoya Okuno, Tomoko Imasaka, Yuichiro Kida, Totaro Imasaka
  • 学会等名: Asianalysis XII
  • 発表場所: Maidashi campus of Kyushu University
  • 年月日: 2013-08-24
• [学会発表] Determination of triacetone triperoxide by gas chromatography/multiphoton/ionization/time -of-flight/mass spectrometry (2013)
  • 著者名/発表者名: Ryota Ezoe, Totaro Imasaka
  • 学会等名: Asianalysis XII
  • 発表場所: Maidashi campus of Kyushu University
  • 年月日: 2013-08-24
• [学会発表] Multiphoton ionization mass spectrometry using a femtosecond laser (2013)
  • 著者名/発表者名: Totaro Imasaka
  • 学会等名: 4^<th> Asia Ociania Mass Spectrometry Conference & 10^<th> TSMS Annual Conference (AOMSC)
  • 発表場所: Taiwan, Taipei
  • 年月日: 2013-06-11
  • 招待講演
• [学会発表] Chirped Pulse Four-Wave Raman Mixing (2013)
  • 著者名/発表者名: Osamu Shitamichi, Totaro Imasaka
  • 学会等名: CLEO/Europe-IQEC 2013
  • 発表場所: Germany, Munich
  • 年月日: 2013-05-15
• [学会発表] Determination of Dioxins at Ultratrace Levels by Femtosecond Multiphoton Ionization/Mass Spectrometry (2012)
  • 著者名/発表者名: Totaro Imasaka, Yu-Ching Chang
  • 学会等名: CLEO 2012
  • 発表場所: USA, San Jose
  • 年月日: 2012-05-10
• [学会発表] Molecules with a One Octave Frequency Domain for the Measurement of the 1-fs Optical Pulse Width (2012)
  • 著者名/発表者名: Tomoko Imasaka, Totaro Imasaka
  • 学会等名: CLEO 2012
  • 発表場所: USA, San Jose
  • 年月日: 2012-05-10
• [学会発表] Raman Amplification by Molecular Phase Modulation Induced for Vibrational Mode of Hydrogen (2012)
  • 著者名/発表者名: Osamu Shitamichi, Shin-ichi Zaitsu, Totaro Imasaka
  • 学会等名: CLEO 2012
  • 発表場所: USA, San Jose
  • 年月日: 2012-05-09
• [学会発表] A Three-Primary-Color Continuous-Wave Laser Generated through Intracavity Raman-Resonant Four-Wave Mixing (2012)
  • 著者名/発表者名: Jumpei Takabayashi, Shin-ichi Zaitsu, Totaro Imasaka
  • 学会等名: CLEO 2012
  • 発表場所: USA, San Jose
  • 年月日: 2012-05-08
• [学会発表] Analysis of Environmental Pollutants by Gas Chromatography/Laser Ionization/Mass Spectrometry (2012)
  • 著者名/発表者名: Totaro Imasaka
  • 学会等名: Workshop in Analytical Conference
  • 発表場所: Germany, Munich
  • 年月日: 2012-04-18
  • 招待講演
• [学会発表] Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry for Analysis of Persistent Organic Pollutants at Femtogram Levels (2012)
  • 著者名/発表者名: Totaro Imasaka
  • 学会等名: Analytical Conference
  • 発表場所: Germany, Munich
  • 年月日: 2012-04-17
  • 招待講演
• [学会発表] Multiphoton Ionization Mass Spectroscopy Using an Ultrashort Optical Pulse (2012)
  • 著者名/発表者名: Totaro Imasaka
  • 学会等名: Seminar in Institute of Water Chemistry
  • 発表場所: Germany, Munich
  • 年月日: 2012-04-16
  • 招待講演
• [学会発表] Analysis of Persistent Organic Pollutants by Gas Chromatography/Laser Multiphoton Ionization Time-of-Flight Mass Spectrometry (2011)
  • 著者名/発表者名: Totaro Imasaka
  • 学会等名: Asianalysis XI
  • 発表場所: Nanjing China
  • 年月日: 2011-08-25
• [学会発表] Gas Chromatography/Multiphoton Ionization/Time-of-Flight Mass Spectrometry for Application to Crude Oil (2011)
  • 著者名/発表者名: Y. Watanabe-Ezoe, Y. Kiten, T. Imasaka
  • 学会等名: 31th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2011)
  • 発表場所: Crown Plaza Brussels
  • 年月日: 2011-08-23
• [学会発表] Quantitative Analysis of Dioxins in soil by Gas Chromatography/Femtosecond Multiphoton Ionization/Time-of-flight Mass Spectrometry (2011)
  • 著者名/発表者名: Yuching Chang, Tomohiro Uchimura, Totaro Imasaka
  • 学会等名: IUPAC International Congress on Analytical Sciences 2011
  • 発表場所: 国立京都国際会館
  • 年月日: 2011-05-26
• [学会発表] Determination of Polybrominated Diphenyl Ethers by Laser Ionization Mass Spectrometry (2011)
  • 著者名/発表者名: Osamu Shitamichi, Tomoko Imasaka, Yuka Watanabe-Ezoe, Tomohiro Uchimura, Totaro Imasaka
  • 学会等名: IUPAC International Congress on Analytical Sciences 2011
  • 発表場所: 国立京都国際会館
  • 年月日: 2011-05-24
• [学会発表] Determination of Polychlorinated Biphenyl Using Gas Chromatography/ Multiphoton Ionization/Time-of-Flight Mass Spectrometry (2011)
  • 著者名/発表者名: Taiki Matsui, Tomohiro Uchimura, Yuka Watanabe-Ezoe, Totaro Imasaka
  • 学会等名: IUPAC International Congress on Analytical Sciences 2011
  • 発表場所: 国立京都国際会館
  • 年月日: 2011-05-24
• [学会発表] Development of a Laser with an Ultimately-Short Optical Pulse Width for "Impulsive" Ionization to Obtain a Molecular Ion in Mass Spectrometry (2011)
  • 著者名/発表者名: Takashi Shimizu, Tomoko Imasaka, Shin-ichi Zaitsu, Tomohiro Uchimura, Totaro Imasaka
  • 学会等名: IUPAC International Congress on Analytical Sciences 2011
  • 発表場所: 国立京都国際会館
  • 年月日: 2011-05-24