ＭＲＩによる軟骨評価ソフトウェアを用いた変形性股関節症関連因子の解明

2013 年度 研究成果報告書

• 研究課題/領域番号: 23659580
• 研究種目: 挑戦的萌芽研究
• 配分区分: 基金
• 研究分野: 放射線科学
• 研究機関: 東京大学
• 研究代表者: 村木 重之 東京大学, 医学部附属病院, 助教 (40401070)
• 研究分担者: 吉村 典子 東京大学, 医学部附属病院, 特任准教授 (60240355) ; 阿久根 徹 東京大学, 医学部附属病院, 特任准教授 (60282662) ; 岡 敬之 東京大学, 医学部附属病院, 特任助教 (60401064)
• 研究期間 (年度): 2011 – 2013
• キーワード: 医療・福祉 / 老化 / MRI / 疫学 / 変形性関節症 / 関節リウマチ

研究概要

本研究では、股関節軟骨の軟骨定量評価用および軟骨質的評価用解析システムを開発し、実臨床に導入した。一方の股関節のみ変化が生じているRA患者20例でdGEMRIC撮像を行い、解析の結果、非荷重部位で正常群と疾患群で差は認められなかったが、荷重部位では正常群と疾患群に有意差を認めた。上述した結果は、Xpにて変化がある荷重部位の軟骨変化を、3次元的に抽出して定量的に求めることが可能になったことを意味している。本年度は開発したソフトウエアの実臨床における運用に成功し、今後の大規模データへのシステムの適用の見通しも立った。

研究成果

• [雑誌論文] Prevalence and progression of radiographic ossification of the posterior longitudinal ligament and associated factors in the Japanese population : A 3-year follow-up of the ROAD study (2014)
  • 著者名/発表者名: Yoshimura N, Nagata K, Muraki S, Oka H, Yoshida M, Enyo Y, Kagotani R, Hashizume H, Yamada H, Ishimoto Y, Teraguchi M, Tanaka S, Kawaguchi H, Toyama Y, Nakamura K, Akune T
  • 雑誌名: Osteoporos Int 巻: 25 ページ: 1089-98
• [雑誌論文] Exercise habits during middle age are associated with lower prevalence of sarcopenia : the ROAD study (2014)
  • 著者名/発表者名: Akune T, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Yoshimura N
  • 雑誌名: Osteoporos Int 巻: 25 ページ: 1081-8
• [雑誌論文] Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort : The Wakayama Spine Study (2014)
  • 著者名/発表者名: Teraguchi M, Yoshimura N, Hashizume H, Muraki S, Yamada H, Minamide A, Oka H, Ishimoto Y, Nagata K, Kagotani R, Takiguchi N, Akune T, Kawaguchi H, Nakamura K, Yoshida M
  • 雑誌名: Osteoarthritis Cartilage 巻: 22 ページ: 104-10
• [雑誌論文] Physical Performance, Bone and Joint Diseases, and Incidence of Falls in Japanese Men and Women : A Longitudinal Cohort Study (2013)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: Osteoporos Int 巻: 24 ページ: 459-466
• [雑誌論文] Risk factors for falls in a longitudinal population-based cohort study of Japanese men and women : The ROAD Study (2013)
  • 著者名/発表者名: Muraki S, Akune T, Ishimoto Y, Nagata K, Yoshida M, Tanaka S, Oka H, Kawaguchi H, Nakamura K, Yoshimura N
  • 雑誌名: Bone 巻: 52 ページ: 516-23
• [雑誌論文] The mid-term efficacy of intra-articular hyaluronic acid injections on joint structure : A nested case-control study (2013)
  • 著者名/発表者名: Oka H, Akune T, Muraki S, Tanaka S, Kawaguchi H, Nakamura K, Yoshimura N
  • 雑誌名: Modern Rheum 巻: 23 ページ: 722-8
• [雑誌論文] Associations between radiographic lumbar spinal stenosis and clinical symptoms in the general population : The Wakayama Spine Study (2013)
  • 著者名/発表者名: Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
  • 雑誌名: Osteoarthritis Cartilage 巻: 21 ページ: 783-8
• [雑誌論文] Profiles of vitamin D insufficiency and deficiency in Japanese men and women : Association with biological, environmental, and nutritional factors and coexisting disorders : The ROAD study (2013)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Morita M, Yamada H, Tanaka S, Kawaguchi H, Nakamura K, Akune T
  • 雑誌名: Osteoporos Int 巻: 24 ページ: 2775-87
• [雑誌論文] Incidence and Risk Factors for Radiographic Knee Osteoarthritis and Knee Pain in Japanese Men and Women : a Longitudinal Population-Based Cohort Study (2012)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: Arthritis Rheum 巻: 64 ページ: 1447-56
• [雑誌論文] The Prevalence of Vertebral Fracture in Asian Men and Women : Comparison between Hong Kong, Thailand, Indonesia and Japan (2012)
  • 著者名/発表者名: Kwok A, Leung J, Chan A, Au B, Lau E, Yurianto H, Yuktanandana P, Yoshimura N, Muraki S, Oka H, Akune T, Leung P
  • 雑誌名: Public Health 巻: 126 ページ: 523-31
• [雑誌論文] Incidence and Risk Factors for Radiographic Lumbar Spondylosis and Lower Back Pain in Japanese Men and Women : The ROAD Study (2012)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: Osteoarthritis Cartilage 巻: 20 ページ: 712-8
• [雑誌論文] Prevalence of cervical cord compression and its association with physical performance in a population-based cohort in Japan : the Wakayama Spine Study (2012)
  • 著者名/発表者名: Nagata K, Yoshimura N, Muraki S, Hashizume H, Ishimoto Y, Yamada H, Takiguchi N, Nakagawa Y, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
  • 雑誌名: SPINE 巻: 37 ページ: 1892-8
• [雑誌論文] Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis : A 3-year follow-up of the ROAD study (2012)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 雑誌名: Osteoarthritis Cartilage 巻: 20 ページ: 1217-26
• [雑誌論文] Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan : The Wakayama Spine Study (2012)
  • 著者名/発表者名: Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
  • 雑誌名: Osteoarthritis Cartilage 巻: 20 ページ: 1103-8
• [雑誌論文] Does mild cognitive impairment affect the occurrence of radiographic knee osteoarthritis? A 3-year follow-up in the ROAD study (2012)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Tanaka S, Akune T
  • 雑誌名: BMJ Open 巻: 2:pii ページ: e001520
  • DOI: 10.1136/bmjopen-2012-001520.
• [雑誌論文] Capacity of endogenous sex steroids to predict bone loss in Japanese men : Ten-year follow-up of the Taiji Cohort Study (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 雑誌名: J Bone Miner Metab 巻: 29 ページ: 96-102
• [雑誌論文] Health-related Quality of Life in Subjects with Low Back Pain and Knee Pain in a Population-Based Cohort Study of Japanese men : The ROAD study (2011)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, En-yo Y, Yoshida M, Saika A, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: SPINE 巻: 36 ページ: 1312-1319
• [雑誌論文] Association of knee osteoarthritis with the accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance in Japanese men and women : The ROAD Study (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 雑誌名: J Rheum 巻: 38 ページ: 921-30
• [雑誌論文] Changes in serum levels of biochemical markers of bone turnover over 10 years among Japanese men and women : associated factors and birth-cohort effect (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 雑誌名: The Taiji Study. J Bone Miner Metab 巻: 29 ページ: 699-708
• [雑誌論文] Association of Occupational Activity with Joint Space Narrowing and Osteophytosis in the Medial Compartment of the Knee : The ROAD study (2011)
  • 著者名/発表者名: Muraki S, Oka H, Akune T, En-yo Y, Yoshida M, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: Osteoarthritis Cartilage 巻: 19 ページ: 840-846
• [雑誌論文] Biochemical markers of bone turnover as predictors for occurrence of osteoporosis and osteoporotic fractures in men and women : Ten-year follow-up of the Taiji cohort study (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 雑誌名: Modern Rheum 巻: 21 ページ: 608-20
• [雑誌論文] Prevalence of falls and its association with knee osteoarthritis and lumbar spondylosis as well as knee and lower back pain in Japanese men and women (2011)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, En-yo Y, Yoshida M, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: Arthritis Care Res 巻: 63 ページ: 1425-31
• [雑誌論文] Independent Association of Joint Space Narrowing and Osteophyte Formation at the Knee with Health-related Quality of Life in Japan : A Cross-sectional Study (2011)
  • 著者名/発表者名: Muraki S, Oka H, Akune T, En-yo Y, Yoshida M, Suzuki T, Yoshida H, Ishibashi H, Tokimura F, Yamamoto S, Nakamura K, Kawaguchi H, Yoshimura N
  • 雑誌名: Arthritis Rheum 巻: 63 ページ: 3859-3864
• [雑誌論文] Association of vitamin D status with knee pain and radiographic knee osteoarthritis (2011)
  • 著者名/発表者名: Muraki S, Dennison E, Jameson K, Boucher B, Akune T, Yoshimura N, Judge A, Arden N, Javaid K, Cooper C
  • 雑誌名: Osteoarthritis Cartilage 巻: 19 ページ: 1301-1306
• [雑誌論文] Reference values for hand grip strength, muscle mass, walking time, and one-leg standing time as indices for locomotive syndrome and associated disability : The second survey of the ROAD study (2011)
  • 著者名/発表者名: Yoshimura N, Oka H, Muraki S, Akune T, Hirabayashi N, Matsuda S, Nojiri T, Hatanaka K, Ishimoto Y, Nagata K, Yoshida M, Tokimura F, Kawaguchi H, Nakamura K
  • 雑誌名: J Orthop Sci 巻: 16 ページ: 768-77
• [雑誌論文] Association of Dietary Intake with Joint Space Narrowing and Osteophytosis at the Knee in Japanese Men and Women : The ROAD Study
  • 著者名/発表者名: Muraki S, Akune T, En-yo Y, Yoshida M, Tanaka S, Kawaguchi H, Nakamura K, Oka H, Yoshimura N
  • 雑誌名: Modern Rheum 巻: (in press)
• [雑誌論文] Prevalence, Incidence, and Progression of Lumbar Spondylosis by Gender and Age Strata
  • 著者名/発表者名: Muraki S, Yoshimura N, Akune T, Sakae Tanaka, Ikuno Takahashi, Saeko Fujiwara
  • 雑誌名: Modern Rheum 巻: (in press)
• [雑誌論文] Incidence of certified need of care in the long-term care insurance system and its risk factors in the elderly of Japanese population-based cohorts : The ROAD study
  • 著者名/発表者名: Akune T, Muraki S, Oka H, Tanaka S, Kawaguchi H, Tokimura F, Yoshida H, Suzuki T, Nakamura K, Yoshimura N
  • 雑誌名: Geriatr Gerontol Int 巻: (in press)
• [雑誌論文] Prevalence of knee pain, lumbar pain and its co-existence in Japanese men and women : The LOCOMO (Longitudinal Cohorts of Motor System Organ) study
  • 著者名/発表者名: Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Omori G, Sudo A, Nishiwaki Y, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K
  • 雑誌名: J Bone Miner Metab 巻: (in press)
• [雑誌論文] Association of knee osteoarthritis with onset and resolution of pain and physical functional disability : The ROAD Study
  • 著者名/発表者名: Muraki S, Akune T, Nagata K, Ishimoto Y, Yoshida M, Tokimura F, Tanaka S, Oka H, Kawaguchi H, Nakamura K, Yoshimura N
  • 雑誌名: Modern Rheum 巻: (in press)
• [雑誌論文] Association of physical activities of daily living with the incidence of certified need of care in the long-term care insurance system of Japan : the ROAD study
  • 著者名/発表者名: Akune T, Muraki S, Oka H, Tanaka S, Kawaguchi H, Tokimura F, Yoshida H, Suzuki T, Nakamura K, Yoshimura N
  • 雑誌名: J Orthop Sci 巻: (in press)
• [雑誌論文] Incidence of disability and its associated factors in Japanese men and women : The Longitudinal Cohorts of Motor System Organ (LOCOMO) study
  • 著者名/発表者名: Yoshimura N, Akune T, Fujiwara S, Shimizu Y, Yoshida H, Nishiwaki Y, Sudo A, Omori G, Yoshida M, Shimokata H, Suzuki T, Muraki S, Oka H, Nakamura K
  • 雑誌名: J Bone Miner Metab 巻: (in press)
• [雑誌論文] Prevalence of diffuse idiopathic skeletal hyperostosis of the whole spine and its association with knee osteoarthritis : the ROAD study
  • 著者名/発表者名: Kagotani R, Yoshida M, Muraki S, Oka H, Hashizume H, Yamada H, Enyo Y, Nagata1 K, Ishimoto Y, Teraguchi M, Tanaka S, Nakamura K, Kawaguchi H, Akune T, Yoshimura N
  • 雑誌名: J Bone Miner Metab 巻: (in press)
• [雑誌論文] The prevalence of cervical myelopathy among subjects with narrow cervical spinal canal in a population-based MRI study : The Wakayama Spine Study
  • 著者名/発表者名: Nagata K, Yoshimura N, Hashizume H, Muraki S, Ishimoto Y, Yamada H, Takiguchi N, Nakagawa Y, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
  • 雑誌名: Spine J 巻: (in press)
• [学会発表] Prevalence of sarcopenia and its association with exercise habits in middle age and physical performance in the elderly participants of Japanese population-based cohorts : the ROAD study (2013)
  • 著者名/発表者名: Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura, K, Oka H, Yoshimura N
  • 学会等名: IOF regionals
  • 発表場所: Hong Kong, China
  • 年月日: 20131212-15
• [学会発表] Risk Factors for Multiple Falls in Japanese Men and Women : The ROAD Study (2013)
  • 著者名/発表者名: Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura, K, Oka H, Yoshimura N
  • 学会等名: 2nd Joint Meeting of the International Bone and Mineral Society (IBMS) and the Japanese Society for Bone and Mineral Research (JSBMR)
  • 発表場所: Kobe, Japan
  • 年月日: 20130528-0601
• [学会発表] Higher levels of serum 25(OH)D prevents the occurrence of osteoporosis, but deteriorates knee osteoarthritis : The ROAD study (2013)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Nakamura K, Tanaka S, Kawaguchi H, Akune T
  • 学会等名: IOF
  • 発表場所: Rome, Italy
  • 年月日: 20130417-21
• [学会発表] The Incidence Rate and Risk Factors for Radiographic Knee Osteoarthritis and Knee Pain : The ROAD Study (2013)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Yoshimura N
  • 学会等名: IOF
  • 発表場所: Rome, Italy
  • 年月日: 20130417-21
• [学会発表] Association of diffuse idiopathic skeletal hyperostosis and bone mineral density and marker of bone metabolism : the ROAD study (2013)
  • 著者名/発表者名: Kagotani R, Muraki S, Oka H, Yoshida M, Hashizume H, Yamada H, Nagata K, Ishimoto Y, Teraguchi M, Tanaka S, Nakamura K, Kawaguchi H, Akune T, Yoshimura N
  • 学会等名: IOF
  • 発表場所: Rome, Italy
  • 年月日: 20130417-21
• [学会発表] Mild Cognitive Impairment Increases The Risk of Knee Osteoarthritis : A 3-Year Follow-Up in The ROAD Study (2012)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T
  • 学会等名: IOF Regionals - 3rd Asia-Pacific Osteoporosis Meeting
  • 発表場所: Kuala Lumpur, Malaysia
  • 年月日: 20121213-16
• [学会発表] Physical Performance, Bone and Joint Diseases, and Incidence of Falls in Japanese Men and Women : The ROAD Study (2012)
  • 著者名/発表者名: Muraki S, Akune T, Tanaka S, Kawaguchi H, Nakamura K, Oka H, Yoshimura N
  • 学会等名: 3rd IOF regionals 2012
  • 発表場所: Kuala Lumpur, Malaysia
  • 年月日: 20121200
• [学会発表] ACCUMULATION OF METABOLIC RISK FACTORS RAISES THE RISK OF OCCURRENCE AND PROGRESSION OF KNEE OSTEOARTHRITIS : THE ROAD STUDY (2012)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Tanaka S, Kawaguchi H, Nakamura K, Akune T
  • 学会等名: EULAR 2012
  • 発表場所: Berlin, German
  • 年月日: 20120600
• [学会発表] Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidemia, and impaired glucose intolerance raises the risk of occurrence and progression of knee osteoarthritis : A 3-year follow-up of the ROAD Study (2012)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 学会等名: IOF-ECCEO 2012
  • 発表場所: Bordeaux, France
  • 年月日: 20120321-24
• [学会発表] The prevalence of lumbar spinal stenosis using mobile MRI in local inhabitants : The ROAD-MRI study (2012)
  • 著者名/発表者名: Ishimoto Y, Yamada H, Nagata K, Hashizume H, Takiguchi N, Yoshida M. Muraki S, Oka H, Akune T, Yoshimura N
  • 学会等名: AAOS
  • 発表場所: San Francisco, USA
  • 年月日: 20120207-11
• [学会発表] The Prevalence Of Cervical Cord Compression Using Mobile MRI In Local Inhabitants : The Road-MRI Study (2012)
  • 著者名/発表者名: Nagata K, Hashizume H, Ishimoto Y, Yamada H, Takiguchi N, Yoshida M. Muraki S, Oka H, Akune T, Yoshimura N
  • 学会等名: AAOS
  • 発表場所: San Francisco, USA
  • 年月日: 20120207-11
• [学会発表] Prevalence of cervical cord compression and its association with physical performance in a large population-based cohort : The ROAD-MRI Study (2011)
  • 著者名/発表者名: Nagata K, Hashizume H, Ishimoto Y, Yamada H, Takiguchi N, Yoshida M. Muraki S, Oka H, Akune T, Yoshimura N
  • 学会等名: CSRS
  • 発表場所: Arizona, USA
  • 年月日: 20111208-10
• [学会発表] Vitamin D Insufficiency and Occurrence of Osteoporosis and Disability : The ROAD Study (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 学会等名: (ASBMR) 33nd Annual Meeting of the American Society for Bone and Mineral Research
  • 発表場所: San Diego, USA
  • 年月日: 20110916-20
• [学会発表] Incidence of Multiple Falls and Risk Factors in a Longitudinal Population-Based Cohort Study in Japan : The ROAD Study (2011)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
  • 学会等名: (ASBMR) 33nd Annual Meeting of the American Society for Bone and Mineral Research
  • 発表場所: San Diego, USA
  • 年月日: 20110916-20
• [学会発表] Incidence and risk factors for radiographic lumbar spondylosis : The ROAD Study (2011)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
  • 学会等名: OARSI for the 2011 World Congress on Osteoarthritis
  • 発表場所: San Diego, USA
  • 年月日: 20110916-20
• [学会発表] Risk factors fot the incidence and progress rate of radiographic knee osteoarthritis in Japanese men and women : The ROAD study (2011)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
  • 学会等名: OARSI for the 2011 World Congress on Osteoarthritis
  • 発表場所: San Diego, USA
  • 年月日: 20110915-18
• [学会発表] Vitamin D insufficiency and deficiency as a risk factor for fast bone loss among elderly men and women : The ROAD study (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 学会等名: 2nd Asia-Pacific Osteoporosis and Bone Meeting
  • 発表場所: Gold Coast, Australia
  • 年月日: 20110904-08
• [学会発表] Risk Factors for Multiple Falls in a Longitudinal Population-Based Cohort Study in Japan : The ROAD Study (2011)
  • 著者名/発表者名: Muraki S, Akune T, Oka H, Nakamura K, Kawaguchi H, Yoshimura N
  • 学会等名: 2nd Asia-Pacific Osteoporosis and Bone Meeting
  • 発表場所: Gold Coast, Australia
  • 年月日: 20110904-08
• [学会発表] Role of neuromuscular function in predicting the occurrence of disability : The ROAD study (2011)
  • 著者名/発表者名: Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T
  • 学会等名: IEA World Congress of Epidemiology
  • 発表場所: Edinburgh, Scotland
  • 年月日: 20110807-11
• [学会発表] Association between lumbar spinal stenosis and physical performance in a population-based cohort in Japan : The Wakayama Spine Study (2011)
  • 著者名/発表者名: Ishimoto Y, Yoshimura N, Muraki S, Yamada H, Nagata K, Hashizume H, Takiguchi N, Minamide A, Oka H, Kawaguchi H, Nakamura K, Akune T, Yoshida M
  • 学会等名: ISSLS
  • 発表場所: Gothenburg, Sweden
  • 年月日: 20110614-18