| 研究実績の概要 |
Preliminary preparation for animal studies was meticulosly conducted. This involved testing of intraperitoneal injection of cancer cells, diligent of mice, careful design of in-vivo setup for ultrasound exposure, and preparing for the monitoring mechanisms.The safety of low-frequency ultrasound for drug delivery was evaluated in vivo. Specifically, pig skin tissue was irradiated with ultrasonic waves (frequency 47 kHz, sound intensity 1.29 W/cm2, diameter 8 mm, for 10 seconds). No apparent tissue damage occurred in the skin tissue under either continuous ultrasound irradiation for 10 seconds or 10 irradiations of 1 second each. This experiment suggests that low-frequency ultrasound is safe for living organisms.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
2: おおむね順調に進展している
理由
A prototype of the device planned for the first year was created. The safety of low-frequency ultrasound on animal skin was also confirmed. Although actual treatment experiments using tumor models could not be conducted, preparations were made for such experiments. Thus, the research is progressing relatively smoothly.
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