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2023 年度 実施状況報告書

気候変動モデリングと集団遺伝解析の融合によるマダニ媒介性感染症の分布拡散予測

研究課題

研究課題/領域番号 23KF0128
研究機関北海道大学

研究代表者

中尾 亮  北海道大学, 獣医学研究院, 准教授 (50633955)

研究分担者 TEO ERNEST  北海道大学, 獣医学研究院, 外国人特別研究員
研究期間 (年度) 2023-09-27 – 2026-03-31
キーワードTicks / Abundance / Geographic distribution / Distribution models / Climate change / Invasive species / Phylogeography
研究実績の概要

Ticks are a big concern to the health of humans and to animals because they transmit a great variety of disease-causing pathogens. For my fellowship, I planned to model the potential geographic range of select ticks, while considering genetics. To that end, since the start of my fellowship, I focused on the tick, Dermacentor auratus. D. auratus is a tick that occurs in the greater part of South and Southeast Asia, and many disease-causing bacteria and viruses have been detected in this tick, including Rickettsia, Borrelia, Kyasanaur forest disease virus and African swine fever virus. Using a species distribution model, I projected the potential geographic range of D. auratus, which will help inform the surveillance of D. auratus and its associated pathogens in South and Southeast Asia.

現在までの達成度 (区分)
現在までの達成度 (区分)

2: おおむね順調に進展している

理由

Although I have only completed one of the many projects that I had planned in the first six months of my fellowship, I am continuously collecting and curating data for at least five other projects which I am working on. Once data collection and data curation for each project is complete, analyses of the curated data will likely be quick, and I foresee that my progress will move on as planned. For these five other projects, I estimate data collection and curation to be about 100%, 90%, 90%, 70%, and 30% for the five projects, in chronological order of the targeted deadlines that I have set for manuscript submissions. Also, I have worked out and tested the materials and methods required for my laboratory experiments, and will start on these experiments soon.

今後の研究の推進方策

I will model the potential geographic range of a few species of ticks of medical and veterinary importance. Noting that some of these species have distinct populations which may transmit different pathogens, I will study, in the laboratory, whether different populations of a single species have different climatic tolerances and climatic profiles. Informed by these data, I will model the potential phylogeographic range of these populations in relation to climate.

I will also study tick-host and tick-pathogen associations and prioritize ticks that are likely to be invasive in Asia Pacific. Simultaneously, I will try to figure out what has allowed certain species of ticks to be invasive and what has prevented other species of ticks to be unable to spread beyond their current geographic range.

次年度使用額が生じた理由

次年度使用額が生じた理由:分布モデル構築が既存データで予想以上に進展し、新たなサンプルの収集、遺伝子情報取得のための消耗品が必要性が低くなったため。
使用計画:別のターゲットマダニ種についてのサンプル採集、遺伝子情報取得のために使用する。

  • 研究成果

    (3件)

すべて 2024 その他

すべて 国際共同研究 (2件) 雑誌論文 (1件) (うち国際共著 1件、 査読あり 1件)

  • [国際共同研究] Georgia Southern University(米国)

    • 国名
      米国
    • 外国機関名
      Georgia Southern University
  • [国際共同研究] The University of Queensland(オーストラリア)

    • 国名
      オーストラリア
    • 外国機関名
      The University of Queensland
  • [雑誌論文] Dermacentor (Indocentor) auratus Supino 1897: Potential geographic range, and medical and veterinary significance2024

    • 著者名/発表者名
      Teo Ernest J.M.、Apanaskevich Dmitry A.、Barker Stephen C.、Nakao Ryo
    • 雑誌名

      Acta Tropica

      巻: 254 ページ: 107197~107197

    • DOI

      10.1016/j.actatropica.2024.107197

    • 査読あり / 国際共著

URL: 

公開日: 2024-12-25  

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