研究実績の概要 |
We have completed three years of this project, with the completion of prospective observational study, case control study and a cross sectional study in Bangladesh on coronary artery disease. Through cross sectional study, we found prevalence of individual risk factors studied was as follows: findings from STEPS1 (behavioral risk factors); 86.9% unhealthy diets, 53.5% tobacco use, 21.7% smoking, 41.4% physical inactivity, 0.7% alcohol consumption; SETPS 2 (physical risk factors): 28.5% elevated blood pressure, 24.1% overweight, 19.7% abdominal obesity; STEPS3 (cardio metabolic risk factors): 10.2% elevated fasting blood glucose, 65.7% low HDL cholesterol, 28.0% raised total cholesterol, 33.8% raised triglyceride. From the prospective observational study and case control study, % of acute coronary syndrome (ACS) was higher in male compared to female. The prevalence of important cardio metabolic risk factors in young ACS patients in Bangladesh is: diabetes (29.89%); hypertension (39.27%); low HDL (51.77%); elevated triglyceride (44.29%); metabolic syndrome (36.13%); overweight (16.3%); obesity (3.26%). 58.7% young ACS patients in Bangladesh are current smoker. No (0); one (1); two (2); three (3) or more than three metabolic abnormality is present in 11%; 28%; 30% as well as in 31% young ACS patients in Bangladesh, respectively. In young STEMI ACS patients in Bangladesh, diabetes is a highly prevalent risk factor compared to the older ACS patients with STEMI. For non-STEMI myocardial infarction, hypertension appears to be the main risk factor in young Bangladeshi population.
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