| 研究実績の概要 |
The prevalence of GDM of Bangladeshi women is 11.5% (urban) and 10.8% (rural) which is statistically non-significant. Prevalence of GDM increases with the increase number of parity. In our study population we found that prevalence of GDM increases with increase of maternal age. Mean blood pressure did not alter in pregnant women with or without GDM in Bangladesh. Percentage of metabolic profile parameters among GDM cases in Bangladesh: high LDL-C (25.8%); low HDL-C (65.5%); hypertriglyceridemia (55.5%); hypercholesterolemia (26.4%); and metabolic syndrome (35.4%). GDM positive cases have 11.62% positive family history of diabetes. More than 90% rural pregnant women in Bangladesh do not know about GDM. Still in Bangladesh, in rural context, around half of the pregnant women do not receive antenatal care. Still the acceptance of institutional delivery rate is very low in rural Bangladesh. Top ranked risk factors for GDM: hypertension, metabolic syndrome, family history of hypertension, family history of diabetes, lack of regular exercise, lack of education, lack of health awareness and increased age in this population. Vascular endothelial growth factor (VEGF) which is now a potential therapeutic and diagnostic target for various diabetic complications is significantly higher in GDM positive cases compared to GDM negative cases. The present study is the first report describing the prevalence of GDM among Bangladeshi rural women and calls for urgent action to stop and prevent the diabetes development in pregnancy and the associated complications both for mother and child.
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